Axiom™ Asia Precision Medicine Research Array Kit, 96-format
Axiom™ Asia Precision Medicine Research Array Kit, 96-format
Applied Biosystems™

Axiom™ Asia Precision Medicine Research Array Kit, 96-format

The Axiom Asia Precision Medicine Research Array (PMRA) is a comprehensive imputation-aware genotyping array with more than 750,000 markers. TheRead more
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Catalog NumberQuantity
9054231 kit
Catalog number 905423
Price (KRW)
5,104,000
Each
-
Add to cart
Quantity:
1 kit
Price (KRW)
5,104,000
Each
Add to cart
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The Axiom Asia Precision Medicine Research Array (PMRA) is a comprehensive imputation-aware genotyping array with more than 750,000 markers. The high-value content on the array is associated with both common and rare diseases for clinical research and disease association studies in East and South Asian populations. This array kit includes the 1x96-format array plate, as well as an Axiom 2.0 Reagent Kit and Axiom GeneTitan Consumables Kit.

The Asia PMRA is ideal for longitudinal cohort studies in precision medicine initiatives, bio-banking, translational research, direct-to-consumer applications, and clinical trials in drug discovery. Markers on the array were selected for the highest genomic coverage from 1000Genomes Project Phase III. Additional gene variants were chosen from broadly referenced public databases, including ClinVar, NHGRI-GWAS catalog, CPIC, PharmaGKB, and PharmaADME. A full description of the array is available in the content flyer.

Highlights:
• Genome-wide association studies (GWAS) imputation module of >540,000 markers from South and East Asian populations
• Broad coverage of common and rare variants associated with human health
• Minimum order size is one kit consisting of one 96-array plate, associated Axiom reagents, and GeneTitan MC consumables sufficient for 96 samples
• The array can be customized with 50,000 markers without affecting the imputation accuracy, or it can be fully customizable as required

Coverage:
• Genome-wide association study (GWAS) variants
• Evidence-based markers of potential clinical relevance (pharmacogenomics, ClinVar, ACMG, exclusive markers)
• Immune-related markers (human leukocyte antigen, killer immunoglobulin-like receptors, autoimmune and inflammatory)
• Functional variants (loss of function, expression quantitative trait loci, nonsynonymous variants, lung phenotypes)
• Disease-related variants (Alzheimer’s disease, cardiometabolic, neurological disorders, diabetes, cancer variants, cardiac variants, other rare variants)
• Tracking-related variants for tracking purposes (fingerprint and sample tracking , mitochondrial, Y chromosome)
Specifications
For Use With (Application)Microarray Analysis
Product LineAxiom™
Quantity1 kit
Shipping ConditionApproved for shipment at Room Temperature or on Wet or Dry Ice
TypeAsia Precision Medicine Research Array Kit
ArrayGenotyping
Format96-array Plate
Number of Arrays96 arrays
Unit SizeEach
Contents & Storage
• One 96-format array plate. Store at 2–8°C.
• One Axiom 2.0 Reagent Kit ((includes reagents and controls for 1 x 96-format array plate). Storage can vary for each reagent; refer to product insert.
• One Axiom GeneTitan Consumables Kit (includes GeneTitan instrument consumables to process 1 x 96 array plate). Store at room temperature.

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Frequently asked questions (FAQs)

All Axiom arrays (except for Axiom Genome-Wide Pan-African Array Set) require a total of 200 ng DNA. The Axiom Genome-Wide Pan-African Array Set requires a total of 300 ng DNA, or 100 ng DNA per array (there are 3 arrays).

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

For information regarding our in-house MRSL requirements, please contact us via phone at 888-362-2447 (in North America) or via email at BioinformaticsServices@thermofisher.com.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

When manipulating genomic DNA, precautions need to be taken to avoid contamination with foreign DNA amplified in other reactions and procedures.
- We recommend that genomic DNA manipulations be performed in a dedicated pre-amplification room or area separate from the main laboratory. This pre-amplification area should have a dedicated set of pipettes and plasticware.
- If a dedicated area is not available, we recommend using a dedicated bench or a dedicated biosafety hood with dedicated pipettes.
- If a dedicated bench or biosafety hood is not available, a set of dedicated pipettes is recommended at the least.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

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