MagniSort™ Streptavidin Positive Selection Beads are designed for the magnetic separation of cells by positive selection. Desired cells are bound by biotinylated antibody and then streptavidin-coated magnetic beads. When placed in a magnetic field, the desired cells are held in place and the undesired cells can be separated by decanting. The clone and concentration of biotinylated antibody to be used to label the desired cells, as well as the concentration of MagniSort™ Streptavidin Positive Selection Beads must be determined empirically. Please refer to the protocol for details on how to optimize both the antibody and MagniSort™ Streptavidin Positive Selection Beads.

The MagniSort™ Streptavidin Positive Selection Beads may also be used to deplete undesired cells using a single antibody. For depletion of cells using multiple antibodies, we recommend the MagniSort™ Streptavidin Negative Selection Beads (cat. MSNB-6002) and protocol.

Reported Application
Magnetic Cell Separation