Type:
Whole Allergen
Whole Allergen
f325 Sheep's milk
f325 Sheep's milk Scientific Information
Display Name:
Sheep's milk
Latin Name:
Ovis spp.
Other Names:
Sheep's milk
Exposure
Allergen Exposure
Sheep's cheese, and other dairy products.
Unexpected exposure
Sometimes included in infant formulas.
Route of Exposure
Main
Sheep's cheese, and other dairy products
Unexpected exposure
Sometimes included in infant formulas.
Clinical Relevance
Sheep’s milk is sometimes recommended as a substitute for cow’s milk in atopic children. However, 15/16 cows´s milk allergic patients had IgE antibodies against sheep’s milk. Crossreactivity with cow’s milk was confirmed in RAST® inhibition (1). Serum albumin and caseins show homology to the corresponding proteins of cow and sheep (2). Milking sheep can cause IgE mediated respiratory problems in milk allergic individuals (3).
Molecular Aspects
Cross-reactivity
Crossreactivity between sheep's milk and cow's milk and whey might be expected.
Milk from other related animals.
Compiled By
Last Reviewed : June 2022
References
- Bernard, H; Wal, JM; Creminon, C; Grassi, J; Yvon, M; Houdebine, LM. Sensitivities of cow’s milk allergic patients to casein fraction of milks from different species. Allergy; 1992;47: 306.
- Spuergin, P; Walter, M; Schiltz, E; Deichman, K; Forster, J; Mueller. Allergenicity of a-caseins from cow, sheep, and goat. Allergy; 1997; 52: 293-298.
- Vargiu; A; Vargiu, G; Locci,F; Del Giacco, Del Giacco, GS. Hypersensitivity reactions from inhalation of milk proteins. Allergy; 1994; 49:386-387.
