What can you get from high pressure ion chromatography?

What can you get from high pressure ion chromatography?

A new level of performance. We made sure each component of our IC systems was built to operate with ease at high backpressures. The speed and resolution achieved from Thermo Scientific Dionex HPIC systems was worth the effort.

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What is high pressure ion chromatography?

Dionex HPIC systems redefine the way ion chromatography is performed due to their continuous operation at up to 5000 psi when configured as a Reagent-Free IC (RFIC) system. This feature allows for the use of high-efficiency 4μm particle-size columns, which provide better performance.

The World's First Universal High-Pressure IC System
Discussion of the Thermo Scientific Dionex ICS-5000+ HPIC system which is able analyze samples at capillary, microbore, or standard flow rates (or any combination of two, in a dual system) at up to 5000 psi.
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        Up NextThe World's First Universal High-Pressure IC System

        Discussion of the Thermo Scientific Dionex ICS-5000+ HPIC system which is able analyze samples at capillary, microbore, or standard flow rates (or any combination of two, in a dual system) at up to 5000 psi.

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    Why develop high pressure ion chromatography capabilities?

    Many of our customers need higher resolution, and one can get significant gains in resolution by reducing an IC column’s particle size. While column efficiency doubles by reducing the particle size from 8µm to 4µm, the smaller particle size increases the column pressure four-fold. Dionex HPIC were designed to operate comfortably at these higher backpressures.

    Dionex IonPac 4µm Columns
    Promotion video for the Dionex IonPac 4µm Columns, their features, and applications
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      Featured column video

      Learn about Thermo Scientific Dionex IonPac 4µm IC columns, their features, and applications.

      How can I balance resolution and speed in my Dionex HPIC system?

      Our 4µm columns are available in microbore (2 mm) and standard bore (4 mm) inner diameters. Different lengths allow you to choose the optimum balance between resolution and throughput.

      • Use the longer, 250 mm length 4µm particle size columns for higher resolution separations of complex sample matrices.
      • Use the shorter, 150 mm length 4µm particle size columns at higher flow rates to increase productivity without sacrificing performance.

      What Dionex HPIC systems are available?

      Integrated, plug-and-play high pressure ion chromatography systems
      Dionex Inuvion Core IC SystemPerform reliable, day-to-day ion analysis while maintaining low operating costs
      Dionex Inuvion IC SystemSimplify your ion analysis with this configurable IC system that has the option to add Reagent-Free IC eluent generation.
      Dionex Integrion HPIC SystemMeet your routine ion analysis demands using the easy-to-use, reliable, integrated IC system
      Modular, highly configurable high pressure ion chromatography systems
      Dionex ICS-6000 Standard Bore and Microbore HPIC SystemsGet significant increases in resolution and throughput in this high-pressure modular IC system for standard bore and microbore columns

      What 4μm particle size IC columns are available?

      Thermo Scientific Dionex IonPac and Thermo Scientific Dionex CarboPac 4 μm Particle-size IC Columns

      IC ColumnApplicationFormat
      Dionex IonPac AS32-Fast-4µmFast analysis of polarizable anions with a simple, isocratic eluentStandard and microbore
      Dionex IonPac AS29-Fast-4µmFast analysis of inorganic anions in drinking waterStandard and microbore
      Dionex IonPac AS28-Fast-4µmFast, high-resolution of trace concentrations of low molecular weight organic acids (glycolate, acetate) and inorganic anionsStandard, microbore, and capillary
      Dionex IonPac AS23-4µmHigh-resolution separation of oxyhalides and inorganic anions in diverse matricesStandard and microbore
      Dionex IonPac AS22-Fast-4µmFast high resolution separation of common inorganic anionsStandard and microbore
      Dionex IonPac AS19-4µmHigh-resolution separation of oxyhalides and inorganic anions in complex sample matricesStandard, microbore, and capillary
      Dionex IonPac AS18-4µm Fast, high-resolution separation of inorganic anions in diverse matricesStandard, microbore, and capillary
      Dionex IonPac AS11-HC-4µm High-resolution separation of organic acids and inorganic anions in complex sample matricesStandard, microbore, and capillary
      Dionex IonPac CS21-Fast-4µmDetermination and quantitation of cationic polar pesticides in food and beverages using IC-MS/MS and IC-HRAM-MSMicrobore
      Dionex IonPac CS19-4µmFast, high-resolution separation of cations and small polar amines in diverse matricesStandard, microbore, and capillary
      Dionex IonPac CS16-Fast-4µmFast, high-resolution separation of short chain amines and disparate ratios of sodium and ammoniumStandard and microbore
      Dionex IonPac CS16-4µmHigh-resolution separation of short chain amines and disparate ratios of sodium and ammoniumStandard, microbore, and capillary
      Dionex IonPac CS12A-5µm High-efficiency and fast analysis of mono- and divalent cationsStandard, microbore, and capillary
      Dionex CarboPac PA300-4µm IC ColumnsAccurate, high-efficiency and high-resolution separations of charged and neutral glycans in complex hetrogenous biological and food samplesMicrobore
      Dionex CarboPac PA210-Fast-4µm IC ColumnsHigh-resolution analysis of mono-, di-, tri-, tetra- and pentasaccharides in various types of food samplesStandard and microbore
      Dionex CarboPac PA20-Fast-4µm IC ColumnsFast and efficient analysis of monosaccharides for therapeutics and food and beverage samplesMicrobore
      Dionex CarboPac SA10-4µm IC ColumnsHigh-resolution, fast and high-capacity separation of mono-and disaccharides in biofuels, foods, and beverages.Standard and microbore

      Can I use other particle size columns with HPIC instruments?

      Yes, of course. Most IC column chemistries can be run on HPIC instruments. Basic column compatibility with instruments is as follows:

      • Standard bore and microbore columns (2–5 mm ID) are for use on the Dionex Inuvion Core IC system, Dionex Inuvion IC system, Dionex Integrion HPIC system or the Dionex ICS-6000 HPIC system.
      • Applications using gradient separations with two or more eluent solutions on standard bore and microbore columns are run on the Dionex ICS-6000 HPIC system configured for gradient separations.
      • Other HPIC systems support isocratic separations or gradient separations achieved by eluent generation.

       

      Chromeleon University

      Here’s a collection of resources to learn about the feature sets that make the Thermo Scientific Chromeleon Chromatography Data System (CDS) both powerful and easy to use.

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