Lentiviral Purification Solutions for Cell Therapy

Advance your downstream lentivirus purification with innovative solutions

Cell and gene therapy vectors derived from lentivirus (LV) offer strong advantages over more conventional retroviral gene delivery systems. With a growing pipeline of LV particle-based therapies comes a prominent need for more efficient manufacturing processes that are meeting the demand of functional LVs required for clinical trials. Explore our unique POROS and affinity-based resins designed to enhance lentiviral purification workflows.

Get help selecting your purification resin. Use this interactive decision-making tool to determine the right chromatography resin for your downstream process.

Purification resin beads

CaptureSelect Lenti-VSVG affinity matrix

This novel affinity matrix has been designed specifically for the purification of VSV-G pseudotyped lentivirus particles. The Lenti-VSVG RUO affinity matrix offers an efficient purification method combined with gentle elution conditions, which helps to retain infectivity of these particles.

POROS Heparin affinity resin

Heparin affinity chromatography is a simple and effective way of purifying proteins containing a heparin binding domain. Due to its important biological function, the domain is often readily accessible, allowing for efficient purification. POROS 50 HE Heparin Affinity resin can be used for the purification of viral vectors containing a Heparin binding site, such as lentivirus or baculovirus.

POROS D50 weak anion exchange resin

Anion exchange chromatography can serve as an ideal solution for the purification of lentiviral particles. The features of POROS D50 resin, a weak anion exchanger, make it suitable for lentivirus capture.

Ordering information

Lentiviral purification solutions

Educational resources to support your lentivirus purification process

Affinity chromatography resin

Using affinity chromatography for the purification of lentiviral particles                                                                                                                                                                                           

Affinity chromatography resin

Advance your lentiviral purification process

Explore more about the Lenti VSV-G resin, designed as an efficient and scalable purification                                                                                             

Advance your lentiviral purification process

Advancing the purification of VSV-G pseudotyped lentiviral vectors by using affinity chromatography

This article describes an affinity resin, suitable for the purification of VSV-G pseudotyped lentivirus particles

Advancing the purification of VSV-G pseudotyped lentiviral vectors by using affinity chromatography

Bioprocess Resin Selection Tool

Use this interactive decision-making tool to determine the right chromatography resin for your purification process.
 

Additional bioprocessing resources

As a trusted partner, we are committed to supporting your journey toward innovative biotech solutions.

Accelerate your therapeutic monoclonal antibody development and manufacturing program.                             

Learn, evaluate, connect.   

 

 

 

 

Connect with a Bioprocessing representative or request more info.                                                               

For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.

1x1 image pixel for data collection