Search Thermo Fisher Scientific
Virus Production Research Services
Collaborating to accelerate your discovery
Advanced design and viral production services enable you to move forward toward your next discovery. From design, synthesis, and production of viral particles, we offer end-to-end services to support every step in your lentivirus (LV) and Adeno-associated virus (AAV) RUO production. Our dedicated staff of R&D scientists and project managers are ready to partner with you and your colleagues to help accelerate your research program. If you’re looking for larger-scale production or seeking CDMO guidance on virus production.
Lentivirus and Adeno-Associated Virus RUO production available
- We offer a complete end-to-end service for the creation of lentiviral and adeno-associated virus expression constructs and virus packaging
- Packaged and titered virus, ready in as little as 4 weeks
- Different promoters and selection markers available for maximum flexibility for transfer plasmid construction
Overview of RUO virus production process
Viral production workflow
- GeneArt proprietary codon optimization algorithm for maximum expression of gene of interest
- Gene synthesis and cloning into vector backbone of interest
- Multiple size deliverables available from mini to mega prep
- 100 mL production scale (please inquire for production scale of up to 1L)
- Uses Gibco LV-MAX or AAV-MAX system CTS-grade for easy scale-up
- Packaged virus particles can be concentrated up to 100X
- Titer determined by p24 ELISA for Lentivirus or qPCR for AAV
- Optional functional titer of viral particles available as a separate assay
- Final deliverable: concentrated virus particles, 1 mL (5 x 200 µL) with an average titer range between 106–109 for lentivirus and 109–1012 for AAV
- GeneArt proprietary codon optimization algorithm for maximum expression of gene of interest
- Gene synthesis and cloning into vector backbone of interest
- Multiple size deliverables available from mini to mega prep
- 100 mL production scale (please inquire for production scale of up to 1L)
- Uses Gibco LV-MAX or AAV-MAX system CTS-grade for easy scale-up
- Packaged virus particles can be concentrated up to 100X
- Titer determined by p24 ELISA for Lentivirus or qPCR for AAV
- Optional functional titer of viral particles available as a separate assay
- Final deliverable: concentrated virus particles, 1 mL (5 x 200 µL) with an average titer range between 106–109 for lentivirus and 109–1012 for AAV
Viral production depends on advanced technologies
The Gibco Lentiviral Production systems are the first optimized systems that provide all the high-quality components you need in a chemically defined, serum-free environment.
Gibco AAV Max Helper-Free AAV Production System Kit
AAV-MAX is a scalable, high-titer platform for suspension AAV production that can help enable you to seamlessly transition from discovery to commercial production.
- High AAV titers
- Scalability
- Animal origin–free (AOF)
- Clonal 293F-derived producer cells
Gibco LV-MAX Lentiviral Production System
LV-MAX is designed to seamlessly transition from discovery to commercial production, offering a scalable and high-yield lentiviral production platform. It is a suspension based, high-density culture of HEK 293–derived Viral Production Cells adapted to a special chemically defined, serum-free and protein-free LV-MAX Production Medium.
- High titers
- Scalability
- Animal origin–free (AOF)
Featured video
Thermo Fisher Cell Biology Services: Virus Production
A short video describing our service capabilities around virus production.
Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.