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siRNA
High quality siRNA reagents for potent gene silencing
RNA interference (RNAi) using small, interfering RNA (siRNA) is the best way to effectively knock down gene expression to study protein function in a wide range of cell types.
- Choose from guaranteed, pre-designed siRNAs targeting human, mouse, or rat
- Validated siRNAs available against key human and mouse targets
- Specificity-enhanced siRNA reduces the likelihood of off-target effects
Choose from our pre-designed siRNA product lines
| Silencer Select siRNA | Stealth RNAi siRNA | Silencer siRNA | |
| RECOMMENDED Highest knockdown, fewest off-targets | Good knockdown, reduced off-targets | Cost-effective, guaranteed siRNA | |
| Potency (recommended working conc.) | 5 nM | 20 nM | 50 nM |
| Silencing guarantee Learn more | 2 of 2 siRNA | 2 of 3 siRNA | 2 of 3 siRNA |
| Target specificity | Highest | High | Moderate |
| Chemical modifications, length |
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| Gene types targeted |
| Protein-coding genes | Protein-coding genes |
| siRNA Libraries |
| Not available | |
| Target species | Human, mouse, rat (Other species: order custom designs) | ||
| Custom siRNA ordering tool | Custom Silencer Select siRNA | Custom Stealth RNAi siRNA | Custom Silencer siRNA |
Libraries
Controls
In vivo RNAi
New to siRNA? Complete the RNAi workflow with optimal siRNA delivery and tools for mRNA knockdown detection!
siRNA videos
Meet the inventor: Susan Magdaleno discusses Silencer Select siRNA technology
Dr. Gavin Robertson describes how Silencer Select siRNA technology is advancing melanoma research.
Shop for everyday lab essentials to power your transfection steps
We've made it easier for you to quickly find and buy products for every step in your transfection workflow.
Resources
Questions?
Technical inquires:
Our Technical Application Scientists are available to help assist you at techsupport@thermofisher.com
Ordering & Order Status inquires:
If you have questions about pre-designed RNAi orders and order status, please contact us at genomicorders@thermofisher.com
If you have any questions about Custom RNAi orders and order status, please contact us at RNAiSupport@thermofisher.com
For Research Use Only. Not for use in diagnostic procedures.