Maple Sycamore Tree
Allergy Facts, Symptoms, and Treatment


The maple sycamore, also called the plane tree, has been introduced into the United States and Canada but is native to western Asia and Europe. The tree is widely known as a sycamore maple, but in Europe it's referred to as simply a sycamore.1 Commonly cultivated as a shade tree, the sycamore maple is moderately allergenic.1,2

Where are maple sycamore trees found?

Native to Europe and western Asia, maple sycamores have been introduced in Canada and the United States. They thrive in Long Island and Cape Cod, where they're considered an invasive species.1

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Are there other allergens I could be sensitized to?*

Many patients with maple sycamore tree allergy can experience symptoms when exposed to other allergens such as tree, weed, or grass pollens, making it difficult to determine which pollen is causing the symptoms, especially when pollen seasons are overlapping. This is called cross-reactivity and occurs when your body's immune system identifies the proteins, or components, in different substances as being structurally similar or biologically related, thus triggering a response. Other respiratory allergens that may cause reactions associated with maple sycamore pollen allergy are tree, weed, and grass pollens.5

If you experience an itchy mouth or throat after eating fresh fruit or raw vegetables, you may suffer from Oral Allergy Syndrome (OAS), sometimes called Pollen Food Allergy Syndrome (PFAS). This condition is caused by your immune system's reaction to similar proteins, or components, found in different allergens. It is quite common, with up to 25 percent of children with allergic rhinitis (i.e., hay fever) also suffering from OAS.4 Common foods involved in OAS for maple sycamore pollen allergy include fruits and vegetables such as peach, banana, hazelnut, peanut, and celery.8

Knowing the proteins, or components, within each allergen that are triggering your symptoms can help guide your management plan. With that in mind, and based on your symptom history, your healthcare provider may suggest something called a specific IgE component test, which can help reveal other pollens you may react to. Results from this test can also help your healthcare provider decide if allergen immunotherapy may reduce your symptoms.5

Already have your specific IgE component test results?

Your component test results will include the name of the components (a series of letters and numbers). Your healthcare provider will likely review the results with you, but here you'll find an at-a-glance breakdown you can use as a reference. Simply match the component names to the list below to see what they mean in terms of symptom management.

rPla a 1

  • Indicates symptoms are caused by maple leaf sycamore (London plane tree) pollen.5
  • Patient may be considered for maple leaf sycamore immunotherapy.7

rBet v 2, rBet v 4

  • Pollen allergy symptoms may be caused by any tree, weed, or grass pollens.7
  • If experiencing PFAS to apple, cherry, hazelnut, etc., birch pollen allergy may be the cause.7

Test results should be interpreted by your healthcare provider in the context of your clinical history. Final diagnosis and decision on further management is made by your healthcare provider.

*These products may not be approved for clinical use in your country. Please work with your healthcare provider to understand availability.

How do I manage my allergy?

The management of allergic rhinitis includes avoidance of relevant allergens, symptomatic treatment, and allergen immunotherapy.4,6,7

  • Check local pollen counts daily and limit time outside when tree-pollen counts are high. Rain helps clear pollen from the air, so the best time to go outside is after a good rain.
  • Delegate outdoor chores whenever possible and wear a pollen mask if you must do outside tasks. 
  • Keep windows closed and use air conditioning instead.
  • Wash bedding at least once a week in hot, soapy water.
  • Wash your clothes after outdoor activities and dry all clothes in a dryer as opposed to line drying outdoors.
  • Bathe and wash your hair every day before bedtime to keep pollen out of your bed.
  • Wipe off any pets to remove pollen before letting them into your home.
  • Ensure everyone removes their shoes before entering your home.
  • Use certified asthma and allergy air filters.
  • Pharmacological treatment, including antihistamines, corticosteroids, decongestants, and saline douches.
  • Allergen immunotherapy as directed by your healthcare provider.

Looking for more allergy info and management tips?

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Common Symptoms

Maple sycamore tree allergy symptoms can be similar to many other pollen allergies and may include:3,4

  • Sneezing
  • Nasal congestion
  • Runny nose
  • Watery eyes
  • Itchy throat and eyes
  • Wheezing

If you're sensitized to maple sycamore trees and have asthma, tree pollen may trigger or worsen asthma symptoms, such as coughing and wheezing.3,4

How do I know if I'm allergic?*

Together with your symptom history, skin-prick testing or specific IgE blood testing can help determine if you are sensitized to a particular allergen. If you are diagnosed with an allergy, your healthcare provider will work with you to create a management plan.

*These products may not be approved for clinical use in your country. Please work with your healthcare provider to understand availability.

Pollen Season

While tree pollen is common in the spring, maple sycamores pollinate in spring to summer, depending on latitude and elevation.2,3

  1. Weber, RW. Allergen of the Month. Ann Allergy Asthma Immunol. 2012(108). Available from: https://www.annallergy.org/article/S1081-1206(12)00077-4/fulltext.
  2. PollenLibrary.com [Internet]. Plymouth Meeting, PA: IMS Health Inc.; 2020. Available from: http://www.pollenlibrary.com/Specie/Acer+pseudoplantanus.
  3. American College of Allergy, Asthma & Immunology [Internet]. Arlington Heights, IL: American College of Allergy, Asthma & Immunology; 2014 [2018 Apr 23]. Available from: https://acaai.org/allergies/types/pollen-allergy.
  4. Roberts, Graham & Xatzipsalti, M & Borrego, Luis & Custovic, Adnan & Halken, Susanne & Hellings, Peter & Papadopoulos, Nikolaos & Rotiroti, G & Scadding, Glenis & Timmermans, Frans & Valovirta, Erkka. (2013). Paediatric rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology. Allergy. 68. 10.1111/all.12235.
  5. Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, Valenta R, Hilger C, Hofmaier S, Aalberse RC, Agache I, Asero R, Ballmer-Weber B, Barber D, Beyer K, Biedermann T, Bilò MB, Blank S, Bohle B, Bosshard PP, Breiteneder H, Brough HA, Caraballo L, Caubet JC, Crameri R, Davies JM, Douladiris N, Ebisawa M, EIgenmann PA, Fernandez-Rivas M, Ferreira F, Gadermaier G, Glatz M, Hamilton RG, Hawranek T, Hellings P, Hoffmann-Sommergruber K, Jakob T, Jappe U, Jutel M, Kamath SD, Knol EF, Korosec P, Kuehn A, Lack G, Lopata AL, Mäkelä M, Morisset M, Niederberger V, Nowak-W?grzyn AH, Papadopoulos NG, Pastorello EA, Pauli G, Platts-Mills T, Posa D, Poulsen LK, Raulf M, Sastre J, Scala E, Schmid JM, Schmid-Grendelmeier P, van Hage M, van Ree R, Vieths S, Weber R, Wickman M, Muraro A, Ollert M. EAACI Molecular Allergology User's Guide. Pediatr Allergy Immunol. 2016 May;27 Suppl 23:1-250. doi: 10.1111/pai.12563. PMID: 27288833.
  6. Asthma and Allergy Foundation of America [Internet]. Arlington, VA: Asthma and Allergy Foundation of America; 2019 Apr 9. Available from: https://community.aafa.org/blog/tips-for-preventing-allergic-reactions-to-tree-and-grass-pollen.
  7. Mayo Clinic [Internet]. Rochester, MN: Mayo Foundation for Medical Education and Research; 2020 Apr 16. Available from: https://www.mayoclinic.org/diseases-conditions/hay-fever/in-depth/seasonal-allergies/art-20048343.