Product References
Schlafen14 Impairs HIV-1 Expression in a Codon Usage-Dependent Manner.
Viruses
Valenzuela C,Saucedo S,Llano M
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Mon Mar 25 00:00:00 UTC 2024
Endosialin-positive tumor-derived pericytes promote tumor progression through impeding the infiltration of CD8+ T cells in clear cell renal cell carcinoma.
Cancer immunology, immunotherapy : CII
Lu T,Zhang J,Lu S,Yang F,Gan L,Wu X,Song H,Liu S,Xu C,Han D,Yang B,Wen W,Qin W,Yang L
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Thu Jun 01 00:00:00 UTC 2023
Distinct SARS-CoV-2 specific NLRP3 and IL-1β responses in T cells of aging patients during acute COVID-19 infection.
Frontiers in immunology
Mahalingam SS,Jayaraman S,Arunkumar A,Dudley HM,Anthony DD,Shive CL,Jacobson JM,Pandiyan P
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Thu Oct 12 00:00:00 UTC 2023
Targeted suppression of Dpt-specific B cells in humanized Rag2- γc- mouse model of HDM allergy.
Scandinavian journal of immunology
Ralchev NR,Kerekov N,Mihaylova N,Kremlitzka M,Hristova D,Dzhorev J,Erdei A,Tchorbanov AI
17-0048-42 was used in Flow cytometry/Cell sorting to investigate Derp1 in dust mite allergies.
Wed Feb 01 00:00:00 UTC 2023
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Tue Oct 18 00:00:00 UTC 2022
Specific transcriptional programs differentiate ICOS from CD28 costimulatory signaling in human Naïve CD4+ T cells.
Frontiers in immunology
Gigliotti CL,Boggio E,Favero F,Incarnato D,Santoro C,Oliviero S,Rojo JM,Zucchelli S,Persichetti F,Baldanzi G,Dianzani U,Corà D
17-0048-42 was used in Flow cytometry/Cell sorting to suggest that ICOS and CD28 costimulatory signals play distinct roles during the activation of naive T cells by modulating distinct sets of immunological and immunometabolic genes.
Fri Sep 23 00:00:00 UTC 2022
Plasma Extracellular Vesicle Subtypes May be Useful as Potential Biomarkers of Immune Activation in People With HIV.
Pathogens & immunity
Bazié WW,Boucher J,Vitry J,Goyer B,Routy JP,Tremblay C,Trottier S,Jenabian MA,Provost P,Alary M,Gilbert C
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Sat Apr 23 00:00:00 UTC 2022
Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma.
Cell reports
Budhu S,Giese R,Gupta A,Fitzgerald K,Zappasodi R,Schad S,Hirschhorn D,Campesato LF,De Henau O,Gigoux M,Liu C,Mazo G,Deng L,Barker CA,Wolchok JD,Merghoub T
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Tue Jan 12 00:00:00 UTC 2021
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.
Journal of neuroinflammation
Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Thu Feb 18 00:00:00 UTC 2021
Diurnal Variation of Plasma Extracellular Vesicle Is Disrupted in People Living with HIV.
Pathogens (Basel, Switzerland)
Bazié WW,Goyer B,Boucher J,Zhang Y,Planas D,Chatterjee D,Routy JP,Alary M,Ancuta P,Gilbert C
17-0048-42 was used in Flow Cytometry to investigate daily variations of large and small EVs, in terms of abundance and microRNA contents in people living with HIV (PLWH) receiving antiretroviral therapy (HIV+ART) and uninfected controls (HIV-).
Sat Apr 24 00:00:00 UTC 2021
In vitro and In vivo CD8+ T Cell Suppression Assays.
Bio-protocol
Xie L,Liu G,Liu Y,Yu Y
17-0048-42 was used in Flow cytometry/Cell sorting to present our adapted protocol for assaying the CD8+CD28- T suppressor cells allospecific suppression of CFSE-labeled responder T cells.
Thu May 20 00:00:00 UTC 2021
Suppression of Human Dendritic Cells by Regulatory T Cells.
Bio-protocol
Huang Q,Lam AJ,Boardman DA,Dawson NAJ,Levings MK
17-0048-42 was used in Flow Cytometry to measure human Treg-mediated suppression of CD80 and CD86 expression on mature, monocyte-derived dendritic cells.
Fri Nov 05 00:00:00 UTC 2021
A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity.
Molecular therapy oncolytics
Hammill JA,Kwiecien JM,Dvorkin-Gheva A,Lau VWC,Baker C,Wu Y,Bezverbnaya K,Aarts C,Heslen CW,Denisova GF,Derocher H,Milne K,Nelson BH,Bramson JL
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Fri Jun 26 00:00:00 UTC 2020
The Potential of Nanobody-Targeted Photodynamic Therapy to Trigger Immune Responses.
Cancers
Beltrán Hernández I,Angelier ML,Del Buono D'Ondes T,Di Maggio A,Yu Y,Oliveira S
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Wed Apr 15 00:00:00 UTC 2020
The TCR Repertoire Reconstitution in Multiple Sclerosis: Comparing One-Shot and Continuous Immunosuppressive Therapies.
Frontiers in immunology
Amoriello R,Greiff V,Aldinucci A,Bonechi E,Carnasciali A,Peruzzi B,Repice AM,Mariottini A,Saccardi R,Mazzanti B,Massacesi L,Ballerini C
17-0048-42 was used in Flow Cytometry to suggest that the majority of public TCRs belonged to virus-associated sequences.
Fri Mar 26 00:00:00 UTC 2021
New Bicistronic TALENs Greatly Improve Genome Editing.
Current protocols in stem cell biology
Martín-Fernández JM,Fleischer A,Vallejo-Diez S,Palomino E,Sánchez-Gilabert A,Ruiz R,Bejarano Y,Llinàs P,Gayá A,Bachiller D
17-0048-42 was used in Flow Cytometry /test) to present data regarding the use of a new, more efficient type of transcription activator-like effector nuclease (TALEN) for gene editing.
Sun Mar 01 00:00:00 UTC 2020
Mesenchymal Stem and Stromal Cells Harness Macrophage-Derived Amphiregulin to Maintain Tissue Homeostasis.
Cell reports
Ko JH,Kim HJ,Jeong HJ,Lee HJ,Oh JY
17-0048-42 was used in Flow Cytometry to demonstrate the role of mesenchymal stem and stromal cell and macrophage cross-talk in post-injury tissue homeostasis in mice.
Tue Mar 17 00:00:00 UTC 2020
Methodology for in vitro Assessment of Human T Cell Activation and Blockade.
Bio-protocol
Podojil JR,Ifergan I,Chiang MY,Meeks JJ,Miller SD
17-0048-42 was used in Flow Cytometry to assess in vitro functionality and mechanism for action in human T cells.
Fri Jun 05 00:00:00 UTC 2020
T-Lymphocyte Subset Distribution and Activity in Patients With Glaucoma.
Investigative ophthalmology & visual science
Yang X,Zeng Q,Göktas E,Gopal K,Al-Aswad L,Blumberg DM,Cioffi GA,Liebmann JM,Tezel G
17-0048 was used in Flow cytometry/Cell sorting to analyse T lymphocytes in patients' blood, to explore the T-cell-mediated component of systemic immunity.
Fri Mar 01 00:00:00 UTC 2019
Expression of CD20 after viral reactivation renders HIV-reservoir cells susceptible to Rituximab.
Nature communications
Serra-Peinado C,Grau-Expósito J,Luque-Ballesteros L,Astorga-Gamaza A,Navarro J,Gallego-Rodriguez J,Martin M,Curran A,Burgos J,Ribera E,Raventós B,Willekens R,Torrella A,Planas B,Badía R,Garcia F,Castellví J,Genescà M,Falcó V,Buzon MJ
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Fri Aug 16 00:00:00 UTC 2019
Absolute lymphocyte count and human adenovirus-specific T-cell immune restoration of human adenovirus infection after kidney transplantation.
Journal of medical virology
Bruminhent J,Apiwattanakul N,Hongeng S,Kantachuvesiri S,Watcharananan SP
17-0048-42 was used in Flow cytometry/Cell sorting to suggest a trend of ALC and HAdV-specific T-cell immune restoration in KT recipients who achieve successful HAdV clearance.
Thu Aug 01 00:00:00 UTC 2019
Accumulation of T-helper 22 cells, interleukin-22 and myeloid-derived suppressor cells promotes gastric cancer progression in elderly patients.
Oncology letters
Chen X,Wang Y,Wang J,Wen J,Jia X,Wang X,Zhang H
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Sun Jul 01 00:00:00 UTC 2018
IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.
Nature communications
Hsieh WC,Hsu TS,Chang YJ,Lai MZ
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Wed Jan 31 00:00:00 UTC 2018
Complement receptor CD46 co-stimulates optimal human CD8+ T cell effector function via fatty acid metabolism.
Nature communications
Arbore G,West EE,Rahman J,Le Friec G,Niyonzima N,Pirooznia M,Tunc I,Pavlidis P,Powell N,Li Y,Liu P,Servais A,Couzi L,Fremeaux-Bacchi V,Placais L,Ferraro A,Walsh PR,Kavanagh D,Afzali B,Lavender P,Lachmann HJ,Kemper C
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Wed Oct 10 00:00:00 UTC 2018
Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells.
Nature communications
Emami-Shahri N,Foster J,Kashani R,Gazinska P,Cook C,Sosabowski J,Maher J,Papa S
17-0048 was used in Flow cytometry/Cell sorting to show the utility of the human sodium iodide symporter (hNIS) for the temporal and spatial monitoring of CAR T-cell behavior in a cancer-bearing host.
Wed Mar 14 00:00:00 UTC 2018
Fingolimod reduces circulating tight-junction protein levels and in vitro peripheral blood mononuclear cells migration in multiple sclerosis patients.
Scientific reports
Annunziata P,Cioni C,Masi G,Tassi M,Marotta G,Severi S
17-0048 was used in Flow cytometry/Cell sorting to study the effects of fingolimod on circulating tight-junction protein levels as well as on peripheral blood mononuclear cells migration.
Thu Oct 18 00:00:00 UTC 2018
Modulation of Endoplasmic Reticulum Stress Controls CD4+ T-cell Activation and Antitumor Function.
Cancer immunology research
Thaxton JE,Wallace C,Riesenberg B,Zhang Y,Paulos CM,Beeson CC,Liu B,Li Z
17-0048 was used in Flow cytometry/Cell sorting to investigate whether the endoplasmic reticulum stress response may be important for CD4+ T-cell activation and whether gp96 is integral to this process.
Tue Aug 01 00:00:00 UTC 2017
Ex vivo culture of human atherosclerotic plaques: A model to study immune cells in atherogenesis.
Atherosclerosis
Lebedeva A,Vorobyeva D,Vagida M,Ivanova O,Felker E,Fitzgerald W,Danilova N,Gontarenko V,Shpektor A,Vasilieva E,Margolis L
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Fri Dec 01 00:00:00 UTC 2017
Hormonal vitamin D up-regulates tissue-specific PD-L1 and PD-L2 surface glycoprotein expression in humans but not mice.
The Journal of biological chemistry
Dimitrov V,Bouttier M,Boukhaled G,Salehi-Tabar R,Avramescu RG,Memari B,Hasaj B,Lukacs GL,Krawczyk CM,White JH
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Fri Dec 15 00:00:00 UTC 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Thu Aug 03 00:00:00 UTC 2017
Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis.
Stem cell reports
Li Y,Brauer PM,Singh J,Xhiku S,Yoganathan K,Zúñiga-Pflücker JC,Anderson MK
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Tue Sep 12 00:00:00 UTC 2017
PD-L1 expression and prognostic impact in glioblastoma.
Neuro-oncology
Nduom EK,Wei J,Yaghi NK,Huang N,Kong LY,Gabrusiewicz K,Ling X,Zhou S,Ivan C,Chen JQ,Burks JK,Fuller GN,Calin GA,Conrad CA,Creasy C,Ritthipichai K,Radvanyi L,Heimberger AB
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2016
A new cell line for high throughput HIV-specific antibody-dependent cellular cytotoxicity (ADCC) and cell-to-cell virus transmission studies.
Journal of immunological methods
Orlandi C,Flinko R,Lewis GK
17-0048 was used in Flow cytometry/Cell sorting to develop a novel rapid fluorometric antibody-mediated cytotoxicity assay for studying HIV-1 specific cytotoxicity.
Wed Jun 01 00:00:00 UTC 2016
Function of Treg Cells Decreased in Patients With Systemic Lupus Erythematosus Due To the Effect of Prolactin.
Medicine
Legorreta-Haquet MV,Chávez-Rueda K,Chávez-Sánchez L,Cervera-Castillo H,Zenteno-Galindo E,Barile-Fabris L,Burgos-Vargas R,Álvarez-Hernández E,Blanco-Favela F
17-0048 was used in Flow cytometry/Cell sorting to investigate the role of prolactin in Treg-mediated immune response, showing that it decreased Treg function in patients with systemic Lupus Erythematosus.
Mon Feb 01 00:00:00 UTC 2016
Tax and Semaphorin 4D Released from Lymphocytes Infected with Human Lymphotropic Virus Type 1 and Their Effect on Neurite Growth.
AIDS research and human retroviruses
Quintremil S,Alberti C,Rivera M,Medina F,Puente J,Cartier L,Ramírez E,Tanaka Y,Valenzuela MA
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
Tumor-derived exosomes regulate expression of immune function-related genes in human T cell subsets.
Scientific reports
Muller L,Mitsuhashi M,Simms P,Gooding WE,Whiteside TL
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Thu Feb 04 00:00:00 UTC 2016
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53.
Science (New York, N.Y.)
Yoon KW,Byun S,Kwon E,Hwang SY,Chu K,Hiraki M,Jo SH,Weins A,Hakroush S,Cebulla A,Sykes DB,Greka A,Mundel P,Fisher DE,Mandinova A,Lee SW
17-0048 was used in Flow cytometry/Cell sorting to reveal that p53-induced expression of death domain 1α regulates the efficient clearance of dead cells and proper immune tolerance.
Fri Jul 31 00:00:00 UTC 2015
RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice.
Molecular therapy. Nucleic acids
Shimizu S,Ringpis GE,Marsden MD,Cortado RV,Wilhalme HM,Elashoff D,Zack JA,Chen IS,An DS
17-0048 was used in Flow cytometry/Cell sorting to demonstrate the potential for effective resistance of sh1005-modified CD4+ T cells to HIV-1 in humanised mice.
Tue Feb 17 00:00:00 UTC 2015
Serum macrophage-derived chemokine/CCL22 levels are associated with glioma risk, CD4 T cell lymphopenia and survival time.
International journal of cancer
Zhou M,Bracci PM,McCoy LS,Hsuang G,Wiemels JL,Rice T,Zheng S,Kelsey KT,Wrensch MR,Wiencke JK
17-0048 was used in Flow cytometry/Cell sorting to study serum macrophage-derived chemokine/CCL22 levels which are associated with glioma risk, CD4 T cell lymphopenia and survival time.
Sat Aug 15 00:00:00 UTC 2015
The HIV-1 gp120 CD4-bound conformation is preferentially targeted by antibody-dependent cellular cytotoxicity-mediating antibodies in sera from HIV-1-infected individuals.
Journal of virology
Veillette M,Coutu M,Richard J,Batraville LA,Dagher O,Bernard N,Tremblay C,Kaufmann DE,Roger M,Finzi A
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Thu Jan 01 00:00:00 UTC 2015
Hyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.
PLoS neglected tropical diseases
Katawa G,Layland LE,Debrah AY,von Horn C,Batsa L,Kwarteng A,Arriens S,W Taylor D,Specht S,Hoerauf A,Adjobimey T
17-0048 was used in Flow cytometry/Cell sorting to provide initial evidence that elevated frequencies of Th17 and Th2 cells form part of the immune network instigating the development of severe onchocerciasis.
Thu Jan 01 00:00:00 UTC 2015
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
17-0048 was used in Flow cytometry/Cell sorting to investigate the role of inductive cues from the vascular niche in coordinating and sustaining haematopoietic specification.
Thu Jul 17 00:00:00 UTC 2014
Reprogramming human endothelial cells to haematopoietic cells requires vascular induction.
Nature
Sandler VM,Lis R,Liu Y,Kedem A,James D,Elemento O,Butler JM,Scandura JM,Rafii S
17-0048 was used in Flow cytometry/Cell sorting to investigate the role of inductive cues from the vascular niche in coordinating and sustaining haematopoietic specification.
Thu Jul 17 00:00:00 UTC 2014
Immunologic human renal allograft injury associates with an altered IL-10/TNF-α expression ratio in regulatory B cells.
Journal of the American Society of Nephrology : JASN
Cherukuri A,Rothstein DM,Clark B,Carter CR,Davison A,Hernandez-Fuentes M,Hewitt E,Salama AD,Baker RJ
17-0048 was used in Flow cytometry/Cell sorting to explore proinflammatory cytokine expression in B-cell subsets.
Tue Jul 01 00:00:00 UTC 2014
Aging and cytomegalovirus infection differentially and jointly affect distinct circulating T cell subsets in humans.
Journal of immunology (Baltimore, Md. : 1950)
Wertheimer AM,Bennett MS,Park B,Uhrlaub JL,Martinez C,Pulko V,Currier NL,Nikolich-Žugich D,Kaye J,Nikolich-Žugich J
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Sat Mar 01 00:00:00 UTC 2014
A comparison of DNA methylation specific droplet digital PCR (ddPCR) and real time qPCR with flow cytometry in characterizing human T cells in peripheral blood.
Epigenetics
Wiencke JK,Bracci PM,Hsuang G,Zheng S,Hansen H,Wrensch MR,Rice T,Eliot M,Kelsey KT
17-0048 was used in Flow cytometry/Cell sorting to demonstrate that a new digital PCR platform offers higher precision, greater accuracy, and technical simplicity in T cell evaluation in comparison to conventional qPCR.
Wed Oct 01 00:00:00 UTC 2014
Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis.
The Journal of infectious diseases
Dutra MS,Béla SR,Peixoto-Rangel AL,Fakiola M,Cruz AG,Gazzinelli A,Quites HF,Bahia-Oliveira LM,Peixe RG,Campos WR,Higino-Rocha AC,Miller NE,Blackwell JM,Antonelli LR,Gazzinelli RT
17-0048 was used in Flow cytometry/Cell sorting to suggest that NOD2 influences the production of IL-17A by CD4 T lymphocytes and might contribute to the development of ocular toxoplasmosis.
Tue Jan 01 00:00:00 UTC 2013
Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950)
Ji N,Somanaboeina A,Dixit A,Kawamura K,Hayward NJ,Self C,Olson GL,Forsthuber TG
17-0048 was used in Flow cytometry/Cell sorting to investigate how blocking the HLA-DR2b allele with small molecule inhibitors may offer a promising therapeutic strategy for the treatment of multiple sclerosis.
Fri Nov 15 00:00:00 UTC 2013
Pathogenicity of pandemic H1N1 influenza A virus in immunocompromised cynomolgus macaques.
PloS one
Pham VL,Nakayama M,Itoh Y,Ishigaki H,Kitano M,Arikata M,Ishida H,Kitagawa N,Shichinohe S,Okamatsu M,Sakoda Y,Tsuchiya H,Nakamura S,Kida H,Ogasawara K
17-0048 was used in Flow cytometry/Cell sorting to investigate the H1N1 influenza A virus in immunocompetent and immunocompromised macaques.
Fri Jul 18 00:00:00 UTC 2014
Experimental infection of macaques with a wild water bird-derived highly pathogenic avian influenza virus (H5N1).
PloS one
Fujiyuki T,Yoneda M,Yasui F,Kuraishi T,Hattori S,Kwon HJ,Munekata K,Kiso Y,Kida H,Kohara M,Kai C
17-0048 was used in Flow cytometry/Cell sorting to reveal a unique translational signature, contrasting CD4(+)Foxp3(+) regulatory T-cells and CD4(+)Foxp3(-) non-regulatory T-cells, which imprints subset-specific protein expression.
Mon Oct 13 00:00:00 UTC 2014
Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine.
PloS one
Nakayama M,Shichinohe S,Itoh Y,Ishigaki H,Kitano M,Arikata M,Pham VL,Ishida H,Kitagawa N,Okamatsu M,Sakoda Y,Ichikawa T,Tsuchiya H,Nakamura S,Le QM,Ito M,Kawaoka Y,Kida H,Ogasawara K
17-0048 was used in Flow cytometry/Cell sorting to examine the efficacy of the H5N1 vaccine candidate Vac-3 against two clades of H5N1 HPAIV strains in cynomolgus macaques.
Tue Mar 03 00:00:00 UTC 2015
A mutation in the human Uncoordinated 119 gene impairs TCR signaling and is associated with CD4 lymphopenia.
Blood
Gorska MM,Alam R
17-0048 was used in Flow cytometry/Cell sorting to show that the V22G mutation of Unc119 represents a novel genetic defect in ICL.
Thu Feb 09 00:00:00 UTC 2012
Prolactin down-regulates CD4+CD25hiCD127low/- regulatory T cell function in humans.
Journal of molecular endocrinology
Legorreta-Haquet MV,Chávez-Rueda K,Montoya-Díaz E,Arriaga-Pizano L,Silva-García R,Chávez-Sánchez L,Moreno-Lafont M,Zenteno-Galindo E,Blanco-Favela F
17-0048 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which prolactin regulates Tregs, showing that it down-regulates CD4+CD25hiCD127low/- regulatory T cell function.
Wed Feb 01 00:00:00 UTC 2012
Epigenetic biomarkers of T-cells in human glioma.
Epigenetics
Wiencke JK,Accomando WP,Zheng S,Patoka J,Dou X,Phillips JJ,Hsuang G,Christensen BC,Houseman EA,Koestler DC,Bracci P,Wiemels JL,Wrensch M,Nelson HH,Kelsey KT
17-0048 was used in Flow cytometry/Cell sorting to develop a new assay to capture glioma immune biology based on quantitative methylation specific PCR (qMSP) of two T-cell genes.
Sat Dec 01 00:00:00 UTC 2012
Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice.
PloS one
Ringpis GE,Shimizu S,Arokium H,Camba-Colón J,Carroll MV,Cortado R,Xie Y,Kim PY,Sahakyan A,Lowe EL,Narukawa M,Kandarian FN,Burke BP,Symonds GP,An DS,Chen IS,Kamata M
17-0048 was used in Flow cytometry/Cell sorting to investigate combination approaches against HIV, showing that short-hairpin RNA-expressing hematopoietic stem/progenitor cells can produce HIV-1-resistant T cells.
Mon Jun 24 00:00:00 UTC 2013
A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy.
PloS one
Schmitt DM,O'Dee DM,Horzempa J,Carlson PE,Russo BC,Bales JM,Brown MJ,Nau GJ
17-0048 was used in Flow cytometry/Cell sorting to examine whether the interaction of genetically modified Francisella tularensis live vaccine strains with human antigen-presenting cells correlates with vaccine effectiveness.
Mon Jun 18 00:00:00 UTC 2012
CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.
Blood
Achour L,Scott MG,Shirvani H,Thuret A,Bismuth G,Labbé-Jullié C,Marullo S
Published figure using CD4 monoclonal antibody (Product # 17-0048-42) in Flow Cytometry
Thu Feb 26 00:00:00 UTC 2009
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation.
Journal of immunology (Baltimore, Md. : 1950)
Lal G,Zhang N,van der Touw W,Ding Y,Ju W,Bottinger EP,Reid SP,Levy DE,Bromberg JS
17-0048 was used in Flow cytometry/Cell sorting to investigate Foxp3 as the master switch for Tregs, showing that expression is regulated by DNA methylation in Tregs.
Thu Jan 01 00:00:00 UTC 2009
