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PB36 recognizes the cytoplasmic domain of integrin subunits alpha-3B and alpha-6B. PB36 reacts with the basement membrane zone and endothelial cells in skin, tubuli in kidney and all vascular and capillary endothelia in brain and heart.
The antibody may be stored at 4 C. For prolonged storage prepare appropriate aliquots and store at or below -20 C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4 C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.
This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Entactin; entactin 1; NID 1; NID-1; Nidogen (enactin); Nidogen precursor (Entactin); Nidogen-1; Nidogen-1;
Gene Aliases: A630025O17; Ent; entactin; entactin-1; Nid; Nid1; nidogen-1
UniProt ID: (Mouse) P10493
Entrez Gene ID: (Mouse) 18073
Molecular Function:
transmembrane signal receptor
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