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Product Details
H00092292-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GLYATL1 (NP_542392, 1 a.a. approximately 333 a.a) full-length human protein.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MFKLCSNKMV SQEGSEVELL VSPGARSEHG RYLQDPIVSI DLSEWLRIIE FLLQGLKVYG SVYHINHGNP FNMEVLVDSW PEYQMVIIRP QKQEMTDDMD SYTNVYRMFS KEPQKSEEVL KNCEIVNWKQ RLQIQGLQES LGEGIRVATF SKSVKVEHSR ALLLVTEDIL KLNASSKSKL GSWAETGHPD DEFESETPNF KYAQLDVSYS GLVNDNWKRG KNERSLHYIK RCIEDLPAAC MLGPEGVPVS WVTMDPSCEV GMAYSMEKYR RTGNMARVMV RYMKYLRQKN IPFYISVLEE NEDSRRFVGQ FGFFEASCEW HQWTCYPQNL VPF
Target Information
The GLYATL1 gene, also known as Glycine-N-Acyltransferase Like 1, is located on chromosome 11q12.1. This gene encodes a member of the glycine-N-acyltransferase family, which is involved in the detoxification pathway by catalyzing the conjugation of acyl-CoA substrates with glycine. The protein encoded by GLYATL1 is localized to the endoplasmic reticulum and is implicated in various cellular processes, including xenobiotic metabolism and mitochondrial glutamine metabolism. Studies have shown that the expression levels of GLYATL1 are significantly associated with cancer prognosis. For example, decreased expression of GLYATL1 has been linked to poor prognosis in patients with clear cell renal cell carcinoma (ccRCC). Furthermore, differential expression analysis has identified GLYATL1 as a potential biomarker in prostate cancer, suggesting its utility in cancer diagnostics and treatment strategies. The gene comprises multiple exons and undergoes alternative splicing, resulting in various transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acyl-CoA:glycine N-acyltransferase-like protein 1; Glutamine N-acyltransferase; Glycine N-acyltransferase-like protein 1; glycine-N-acyltransferase-like 1
Gene Aliases: GATF-C; GLYATL1; GNAT
UniProt ID: (Human) Q969I3
Entrez Gene ID: (Human) 92292
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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