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The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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Protein Aliases: 256 kDa golgin; 72.1 protein; centrosome-related protein F46; golgi autoantigen, golgin subfamily a, 4; Golgin subfamily A member 4; golgin-240; Golgin-245; Protein 72.1; Trans-Golgi p230
Gene Aliases: CRPF46; GCP2; GOLG; GOLGA4; MU-RMS-40.18; p230
UniProt ID: (Human) Q13439
Entrez Gene ID: (Human) 2803
Molecular Function:
membrane traffic protein
membrane trafficking regulatory protein
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