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Product Details
10948-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SUB1 Fusion Protein Ag1390 (1-127 aa encoded by BC009610)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.24 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody recognize 14-16 kDa (P14 or P15), 20 kDa (phospho form) and 30 kDa (Dimer form).
Immunogen sequence: MPKSKELVS SGSSGSDSDS EVDKKLKRKK QVAPEKPVKK QKTGETSRAL SSSKQSSSSR DDNMFQIGKM RYVSVRDFKG KVLIDIREYW MDPEGEMKPG RKGISLNPEQ WSQLKEQISD IDDAVRKL (1-127 aa encoded by BC009610)
Target Information
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: activated RNA polymerase II transcription cofactor 4; Activated RNA polymerase II transcriptional coactivator p15; p14; PC4; Positive cofactor 4; pR-ET2 encoded oncodevelopmental protein; RNA polymerase II transcriptional coactivator; Single-stranded DNA-binding protein p9; SUB1 homolog; TIS7
Gene Aliases: AI842364; p14; P15; P9; PC4; RPO2TC1; SUB1
UniProt ID: (Human) P53999, (Rat) Q63396, (Mouse) P11031
Entrez Gene ID: (Human) 10923, (Rat) 192269, (Mouse) 20024
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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