Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Positive Control: A549
Predicted Reactivity: Rat (97%), Xenopus laevis (88%), Chicken (98%), Rhesus Monkey (100%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
TWSG1 may be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: twisted gastrulation homolog 1; Twisted gastrulation protein homolog 1
Gene Aliases: 1810013J15Rik; 9030422N06Rik; AW552143; D17Ertd403e; PSEC0250; TSG; Twg; TWSG1
UniProt ID: (Human) Q9GZX9, (Mouse) Q9EP52
Entrez Gene ID: (Human) 57045, (Mouse) 65960
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