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Application
Product Details
23277-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Trefoil factor 3 Fusion Protein Ag9543 (1-80 aa encoded by BC017859)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAARALCML GLVLALLSSS SAEEYVGLSA NQCAVPAKDR VDCGYPHVTP KECNNRGCCF DSRIPGVPWC FKPLQEAECT F (1-80 aa encoded by BC017859)
Target Information
Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. Trefoil peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain and clustered in human chromosome 21q22.3. Trefoil Factor 3 (TFF3) is one of three trefoil peptides secreted by epithelial cells that line mucus membranes in the large and small intestines and lower respiratory tract. TFF3 is mainly active as a disulfide-linked homodimer and may have a role in promoting cell migration in healing processes. It is involved in the maintenance and repair of the intestinal mucosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hITF; hP1.B; Intestinal trefoil factor; Polypeptide P1.B; Trefoil factor 3; trefoil factor 3 (intestinal)
Gene Aliases: ITF; P1B; TFF3; TFI
UniProt ID: (Human) Q07654
Entrez Gene ID: (Human) 7033
Performance Guarantee
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