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Understanding electron microscopy principles
Thermo Fisher Scientific is your premier partner for imaging with electron microscopy, which can help you reveal and characterize hidden structures to push the boundaries of science and innovation. Our unique workflows bolster research, development, and production solutions.
Electron microscopes are used for a variety of applications across scientific and industrial fields. They uncover the structure of specimens at the nanoscale, providing a link between composition, structure, and performance that can support both technological advances such as smaller and faster computers, chemical sensors, and high-performance materials as well as ground-breaking biological discoveries, targeted drug design, and much more.
Electron microscopes use a beam of electrons to create an image of your specimen, helping you visualize structures from microns down to the molecular and atomic levels. Scanning electron microscopes (SEMs) scan a focused beam of electrons across the surface of a specimen and capture the scattered electrons to reveal surface topography, contrast, and compositional information. Focused ion beam-scanning electron microscopes (FIB-SEMs) combine the capabilities of both a focused ion beam (FIB) system and a SEM in a single platform for both precise material modification and high-resolution imaging. Transmission electron microscopes (TEMs) transmit a beam of electrons through a very thin specimen to image the internal structure of the specimen and fine details, such as atomic arrangements and crystal structures.
Electron microscopy applications
Materials Science Research using Electron Microscopy
Innovative materials play essential roles in safety, clean energy, transportation, human health, and industrial productivity. To fuel continued innovation, researchers must deepen their understanding of the physical and chemical properties of materials from the macroscale to the nanoscale. Whether discovering new materials, solving analytical problems, improving processes, or assuring product quality, electron microscopy can provide insight at all scales and modalities. Materials science discoveries can help researchers correlate structural properties with functional performance, which in turn can help commercial enterprises innovate while saving time and money.
Semiconductor Manufacturing & Analysis using Electron Microscopy
Consumer demand is driving the electronics industry to produce faster, smaller, cheaper, and more power efficient portable devices. Device manufacturers must place a high premium on time to market, reliability, and device performance. On an operational level, this means working with shrinking geometries, new materials, and novel architectures. At this level of innovation, critical dimensions are simply too small to see or characterize with other tools. Electron microscopy, with its new, more productive, and more sophisticated workflows, makes this work possible.
Life Science Research & Drug Design using Electron Microscopy
Uncover more inside your cells and tissues with ultrastructural analyses. Dive deeper into protein structure determination and protein localization at the nanometer level to unlock mechanistic insights or design better drugs. Investigate the 3D structure of cells, tissues, and organisms using 3D volume electron microscopy. Perform large area, high-resolution screens of cell and tissue sections, then zoom in for minute, intracellular details for research in all fields of cell biology, neurobiology, rational drug design, plant biology, histology, and pathology research.
With complete workflow solutions for scanning electron microscopes, transmission electron microscopes, and focused ion beam-scanning electron microscopes, Thermo Fisher Scientific combines high-resolution imaging with physical, elemental, chemical, and electrical analysis across scales and modes.
- Scanning electron microscopes
- Desktop scanning electron microscopes
- Transmission electron microscopes
- DualBeam FIB-SEM instruments
- XPS instruments
- Electrical failure analysis systems
- Circuit edit systems
- Sample preparation equipment
- 3D visualization, analysis software
- EM system software
- Upgrades & accessories
- Electron microscopy service and support
Learn more about electron microscopy
Electron microscopy learning center
Electron microscopy resources and reference materials for microscopy novices, experts, and everyone in between. The electron microscopy learning center provides a variety of informational and educational resources on electron microscopy for students, educators, or anyone that simply wants to learn more about this fascinating technology.
NanoPort electron microscopy facilities
Our NanoPort facilities, conveniently located around the world, are centers of excellence that offer demonstrations, testing, and training for our latest electron microscopy technologies. Whether you are new to the capabilities of electron microscopy, looking to stay up to date with the latest advances, or are interested in testing your samples on our instruments, our NanoPort facilities offer a range of services to help you learn more, get up to speed, and stay at the forefront of research.
Electron microscopy services
To ensure optimal system performance, we provide you access to a world-class network of field service experts, technical support, and certified spare parts.
Electron microscopy support and resources
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