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NeutrAvidin Protein
NeutrAvidin Protein
Thermo Scientific™

NeutrAvidin Protein

Thermo Scientific™ NeutrAvidin Protein is a specially-prepared form of avidin that decreases background in biotin-binding.Features include:• Near-neutral isoelectric point—pI =Read more
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Catalog NumberQuantity
310551000 mg
3100010 mg
31050100 mg
Catalog number 31055
Price (USD)
3,920.00
Each
In stock
Add to cart
Quantity:
1000 mg
Recurring order eligible. Learn more »
Price (USD)
3,920.00
Each
Add to cart
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Thermo Scientific™ NeutrAvidin Protein is a specially-prepared form of avidin that decreases background in biotin-binding.

Features include:
Near-neutral isoelectric point—pI = 6.3, more neutral than native avidin
Nearly devoid of glycosylation—decreased possibility of lectin binding compared to native avidin
No RYD recognition sequence—no known off-target binding domains like streptavidin
Affordable—significantly less expensive than streptavidin

NeutrAvidin Protein is deglycosylated native avidin from egg whites. Removal of the excess carbohydrate by an exclusive process yields a protein with a more neutral isoelectric point and less nonspecific binding properties. Purified NeutrAvidin Protein provides exceptional performance in western blot, ELISA, and IHC applications that require biotin-binding probes. Assay specificity, sensitivity, and signal-to-noise ratios with NeutrAvidin Protein are generally equivalent or better than with the significantly more expensive streptavidin.

Avidin is a glycoprotein found in the egg white and tissues of birds, reptiles, and amphibia. The biotin-binding protein contains four identical subunits having a combined mass of 67,000-68,000 daltons. Removing the glycosylation from avidin yields NeutrAvidin Protein with a mass of 60,000 daltons. Carbohydrate-based lectin binding is reduced to undetectable levels, yet biotin-binding affinity is retained. NeutrAvidin Protein offers the advantages of a neutral pI to minimize nonspecific adsorption, along with lysine residues that remain available for derivatization or other customized conjugation. NeutrAvidin Protein yields the lowest nonspecific binding among the known biotin-binding proteins. The specific activity for biotin binding is approximately 14 μg/mg of protein, which is near the theoretical maximum activity.

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For Research Use Only. Not for use in diagnostic procedures.
Specifications
Label or DyeUnlabeled
Protein FamilyAvidin
Quantity1000 mg
Target MoleculeBiotin
FormSolid
Unit SizeEach
Contents & Storage
Upon receipt store product 4°C. Product is shipped at ambient temperature.
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Frequently asked questions (FAQs)

What is the shelf life of NeutrAvidin Protein?

NeutrAvidin Protein is covered under our general 1-year warranty and is guaranteed to be fully functional for 12 months from the date of shipment, if stored as recommended (4 degrees C). Please see section 8.1 of our Terms & Conditions of Sale for more details.

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Certificates

Lot #Certificate TypeDateCatalog Number(s)
3213206Certificate of AnalysisJul 07, 202531055
3211891Certificate of AnalysisMay 28, 202531050
3212182Certificate of AnalysisApr 25, 202531000
AA403567Certificate of AnalysisFeb 12, 202531055, DNU-31055
ZI403566Certificate of AnalysisOct 22, 202431055
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