Orlistat, 98%
Orlistat, 98%
Orlistat, 98%
Thermo Scientific Chemicals

Orlistat, 98%

CAS: 96829-58-2 | C29H53NO5 | 495.75 g/mol
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Catalog number J62999.MC
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Quantity:
100 mg
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Price (USD)
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Specifications
CAS96829-58-2
Chemical Name or MaterialOrlistat
ColorWhite
Formula Weight495.73
IUPAC Name(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate
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Ask our AI about this Product
Orlistat, used in obesity research, is a pancreatic lipase inhibitor that acts locally in the gastrointestinal tract to inhibit lipase. More detailed experiments show that gradually THL affects the retinoblastoma protein pathway and leads to cell-cycle arrest at G1/S boundary. Lipase Inhibitor, THL is an inhibitor of pancreatic and gastric lipase, as well as carboxyl ester lipase (CEL) and diacylglycerol lipase-α (DAGLα). Lipase Inhibitor, THL also activates caspase-3.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Orlistat, used in obesity research, is a pancreatic lipase inhibitor that acts locally in the gastrointestinal tract to inhibit lipase. More detailed experiments show that gradually THL affects the retinoblastoma protein pathway and leads to cell-cycle arrest at G1/S boundary. Lipase Inhibitor, THL is an inhibitor of pancreatic and gastric lipase, as well as carboxyl ester lipase (CEL) and diacylglycerol lipase-α (DAGLα). Lipase Inhibitor, THL also activates caspase-3.

Solubility
Soluble in DMSO (19 mg/mL), ethanol (20 mg/mL), and DMF (20 mg/mL).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Khedidja B & Abderrahman L Selection of orlistat as a potential inhibitor for lipase from Candida species. Bioinformation.2011, 7, (3), 125-9.
  2. Kridel SJ et al. Orlistat is a novel inhibitor of fatty acid synthase with antitumor activity. Cancer Res.2011, 64, (6), 2070-5 .
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Lot #Certificate TypeDateCatalog Number(s)
P24L002Certificate of AnalysisMar 26, 2025J62999.MC, J62999.MD, J62999.MF
N21L054Certificate of AnalysisFeb 24, 2025J62999.MC, J62999.MD, J62999.MF
N21L055Certificate of AnalysisFeb 24, 2025J62999.MC, J62999.MD, J62999.MF
Z17K045Certificate of AnalysisDec 26, 2024J62999.MC, J62999.MD, J62999.MF
Z20K062Certificate of AnalysisDec 26, 2024J62999.MC, J62999.MD, J62999.MF
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