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POROS™ XQ Strong Anion Exchange Resin
Thermo Scientific™ POROS™ XQ resin is a next-generation, high-capacity, high-resolution, salt-tolerant, strong anion exchange resin that that enables >140 mg/mL dynamic binding capacity in the presence of up to 6.6 mS/cm NaCl, while delivering exceptional separation performance.
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Catalog number 4467816
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Quantity:
10 L
POROS XQ resin is a next-generation, high-capacity, high-resolution, salt-tolerant, strong anion exchange resin that that enables >140 mg/mL dynamic binding capacity in the presence of up to 6.6 mS/cm NaCl, while delivering exceptional separation performance. A major improvement to the performance of traditional anion exchangers, POROS XQ resin sets the standard for strong anion exchange chromatography in both bind & elute or flow-through modes of operation.
Features of POROS XQ resin include:
- High dynamic binding capacity leading to reduced column size, smaller footprint, decreased water and buffer usage, and reduced cycling
- High resolution supporting improved product yield and purity, ultimately improving the cost of goods for the molecule being produced
- Robust salt tolerance allowing enhanced process design flexibility and streamlining of process flow
- Low operating back pressure and linear pressure versus flow responses driving flexible scalability
- Rigid polymeric bead with covalent surface chemistry for easier handling and packing, and superior physical and chemical stability enabling a more robust downstream purification process
Dynamic Binding Capacity
POROS XQ resin has a high binding capacity of more than 140 mg/mL at 5% breakthrough, over a broad range of process conditions, with superior binding capacity across a broad range of pH and salt conditions. Higher dynamic binding capacity was achieved by optimizing the base bead pore structure and surface chemistry.
High Resolution
Using an optimized 50 μm particle size, POROS XQ resin maintains the superior resolving capacity of the POROS resins, overcoming the challenging impurity levels associated with high titer processes. Resolution remains consistent across a wide range of operating flow rates.
Robust Salt Tolerance
POROS XQ resin has high and consistent protein capacity across a broad range of salt concentrations up to 140 mg/mL at 50 mM NaCl (6.6 mS/cm conductivity). The ability to load columns under higher conductivity reduces or helps eliminate the dilution of column feed streams or the removal of unit operations, such as tangential flow filtration.
Specifications
PackagingBottle
Particle Size50 μm
Product LinePOROS™
Recommended StorageRoom Temperature
Stationary PhaseStrong anion exchange
Quantity10 L
Unit SizeEach
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Lot #Certificate TypeDateCatalog Number(s)
XQ-164Certificate of AnalysisJul 14, 20254467818
XQ-163Certificate of AnalysisJul 11, 20254467820
XQ-164Certificate of AnalysisJul 07, 20254467816
XQ-163Certificate of AnalysisJun 26, 20254467817
XQ-161Certificate of AnalysisJun 19, 20254467818
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Notice to Purchaser: The purchase of this product conveys to the purchaser the limited, non-transferable right to use the purchased amount of the product, under intellectual property rights that are owned and/or controlled by Life Technologies and relate specifically to the product, to perform (a) internal research for the sole benefit of the purchaser; (b) quality control testing conducted by the purchaser on a fee for service or contract basis for or on behalf of third parties; and (c) performance of research or manufacturing services conducted by the purchaser on a fee for service or contract basis for or on behalf of third parties. The purchase of this product does not grant the purchaser any additional rights, including, without limitation, the right to transfer or resell the product in any form, the right to use the product as a therapeutic agent or diagnostics test component, or to use the product to perform tests other than what is indicated in this Limited Use Label License on a contract or fee per test basis for or on behalf of third parties. For information on obtaining additional rights, please contact outlicensing@thermofisher.com, Licensing and Commercial Supply, Thermo Fisher Scientific, 5823 Newton Drive, Carlsbad, CA, 92008, United States.
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