Nalidixic acid, 99.5%, Thermo Scientific Chemicals
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Nalidixic acid, 99.5%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Nalidixic acid, 99.5%, Thermo Scientific Chemicals

Nalixidic acid, or nalixidin, CAS # 389-08-2, is a quinolone antibiotic used to inhibit DNA gyrase and prevent cell division.
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数量:
100 g
5 g
25 g
パッケージ:
Glass bottle
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製品番号（カタログ番号） 169901000
価格（JPY）/ Each
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数量:
100 g
パッケージ:
Glass bottle
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化学物質識別子
CAS389-08-2
IUPAC Name1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Molecular FormulaC12H12N2O3
InChI KeyMHWLWQUZZRMNGJ-UHFFFAOYSA-N
SMILESCCN1C=C(C(O)=O)C(=O)C2=CC=C(C)N=C12
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仕様Specification Sheetスペックシート
Appearance (Color)White to light yellow
Titration with NaOH>=99.4 %
Infrared spectrumConforms
Appearance (Form)Powder
Melting point225°C to 231°C
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Nalixidic acid is a synthetic quinolone that is a monocarboxylic acid composed of 1,8-naphthyridine substituted with carboxylic acid, ethyl, and methyl groups

• Nalixidic acid is a DNA gyrase inhibitor that prevents DNA synthesis and subsequent cell divisions

Applications

• Nalixidic acid is primarily effective against gram-negative bacteria

• It may be useful for bacterial resistance studies and laboratory research on drug allergies and cross-reactivity

• Nalixidic acid is suitable for high-performance liquid chromatography (HPLC) and related biochemistry laboratory applications

RUO – Research Use Only

General References:

  1. Kumar, Y.; Sharma, A.; Mani, K.R. Characterization of antimicrobial resistance markers & their stability in Salmonella enterica serovar Typhi. Indian J Med Res. 2017, 146, S9-S14.
  2. Morales-Irigoyen, E.E.; de Las Mercedes Gómez-Y-Gómez, Y.; Flores-Moreno, J.L.; Franco-Hernández, M.O. A bionanohybrid ZnAl-NADS ecological pesticide as a treatment for soft rot disease in potato (Solanum tuberosum L.). Environ Sci Pollut Res Int. 2018, 25(22), 21430-21439.