Dynabeads™ Carboxylic Acid for RNA Purification
Dynabeads™ Carboxylic Acid for RNA Purification
Invitrogen™

Dynabeads™ Carboxylic Acid for RNA Purification

Dynabeads Carboxylic Acid for RNA Purification are intended for simple, scalable, and automatable purification of crude RNA produced by in詳細を見る
製品番号(カタログ番号)数量
65021D10 mL
65020D2 mL
製品番号(カタログ番号) 65021D
価格(JPY)
-
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数量:
10 mL

Dynabeads Carboxylic Acid for RNA Purification are intended for simple, scalable, and automatable purification of crude RNA produced by in vitro transcription (IVT) (figure below) in combination with Dynabeads RNA Binding Buffer (available separately). It is particularly suitable where flexibility and high purity are required, such as in the discovery phase of RNA-based vaccines and therapeutics development.

The product contains monosized (1 μm), monodispersed, paramagnetic beads characterized by high speed-to-magnet and high pellet stability. The concentration of the beads is 10 mg/mL. The beads are stored in purified water and may be recycled for at least six times.

Features of Dynabeads Carboxylic Acid for RNA Purification include:

  • Efficiency—reuse the beads to help reduce the cost and time in a simple workflow
  • Scalability—swap between manual and automated workflows to match your required scale (micrograms to grams of mRNA) and throughput
  • Quality—help ensure a safe and flexible supply of magnetic beads to navigate from RNA-based drug discovery research to commercial manufacturing with counterpart solutions (available via the OEM commercial supply) without incurring extra time or costs from switching technology or raw material

Overview of the workflow

Crude RNA from an IVT reaction step is mixed with the Dynabeads Carboxylic Acid for RNA Purification, and Dynabeads RNA Binding Buffer (not included) is added. The RNA binds to the bead surface and the remaining components of the reaction mixture are removed by a magnet (see thermofisher.com/magnets) and discarding of the supernatant (figure below).

The beads are offered as a stand-alone product. They are also included in the Dynabeads RNA Purification and Dynabeads In Vitro Transcription and RNA Purification kits.

Automation-ready for use with KingFisher purification systems

The 1-μm magnetic beads are ideal for high-throughput screening. The process can be automated using liquid handlers or any of our KingFisher sample purification systems. The scripts for KingFisher Flex and KingFisher Apex automated purification workflows are available from our website.

Commercial supply

To learn more about counterpart products and support documentation available for GMP-compliant manufacturing of mRNA vaccines and therapeutics, visit: thermofisher.com/dynabeadsmrna

仕様
認証/コンプライアンスISO9001 and ISO13485
Brown
濃度10 mg/mL
直径(メートル法)1 μm
使用対象(アプリケーション)Synthetic RNA
使用対象 (装置)KingFisher™ Sample Purification System, DynaMag™ magnets
高スループット適合性Yes
材料Magnetic Polystyrene
製品ラインDynabeads™, Dynabeads™
製品タイプCarboxylic Acid Magnetic Bead
数量10 mL
品質保持期間36 Months (from date of manufacture)
出荷条件Ambient Temperature
均一性Monosized 1 μm (CV <5%)
容量(メートル法)10 mL
Isolation Technology磁気ビーズ
Unit SizeEach
組成および保存条件
Dynabeads magnetic beads are supplied in purified water. Store at 2°C to 8°C.

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