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Zenon™ pHrodo™ iFL IgG Labeling Reagents
New Zenon pHrodo Deep Red Labeling Reagents are superior in three ways: improved bioconjugation for brighter signal, redesigned protein for robust screening regardless of IgG isotype, and a new, more sensitive fluorophore.
Zenon™ pHrodo™ iFL IgG Labeling Reagents
Zenon™ pHrodo™ iFL IgG Labeling Reagents
Zenon™ pHrodo™ iFL IgG Labeling Reagents
Zenon™ pHrodo™ iFL IgG Labeling Reagents
Invitrogen™

Zenon™ pHrodo™ iFL IgG Labeling Reagents

Zenon™ pHrodo™ iFL Green-labeled or Red-labeled Fab fragments (i.e. labeling reagent) are directed against the Fc portion of an intact IgG primary antibody to form a labeling complex.
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카탈로그 번호수량라벨 또는 염료색상
Z25612250 μLHumanpHrodo iFL RedRed
Z25618250 μLHumanpHrodo Deep RedDeep Red
Z25622250 μLMousepHrodo Deep RedDeep Red
Z25611250 μLHumanpHrodo iFL GreenGreen
Z25610250 μLMousepHrodo iFL RedRed
Z25609250 μLMousepHrodo iFL GreenGreen
Z256231.2 mLHumanpHrodo Deep RedDeep Red
Z256141.2 mLHumanpHrodo iFL RedRed
Z256131.2 mLHumanpHrodo iFL GreenGreen
Z256241.2 mLMousepHrodo Deep RedDeep Red
Z256261.2 mLMousepHrodo RedRed
Z256251.2 mLMousepHrodo GreenGreen
카탈로그 번호 Z25612
제품 가격(KRW)
1,696,000
Online offer
Ends: 30-Sep-2025
1,785,000
할인액 89,000 (5%)
250 μL
재고 있음
카트에 추가하기
수량:
250 μL
종:
Human
라벨 또는 염료:
pHrodo iFL Red
색상:
Red
Recurring order eligible. Learn more »
제품 가격(KRW)
1,696,000
Online offer
Ends: 30-Sep-2025
1,785,000
할인액 89,000 (5%)
250 μL
카트에 추가하기
Ask our AI about this Product
Streamline antibody-drug conjugate screening campaigns with Invitrogen Zenon pHrodo IgG Labeling Reagents to screen for antibody internalization. These reagents provide rapid, scalable antibody labeling and give a bright fluorescence-based indication of antibody uptake and trafficking in target cells when analyzed by flow cytometry, fluorescence microscopy, or high-content screening.

Zenon™ pHrodo™ iFL Green-labeled or Red-labeled Fab fragments (i.e. labeling reagent) are directed against the Fc portion of an intact IgG primary antibody to form a labeling complex. Formation of the Fab–antibody complex occurs in fewer than 5 minutes. Because the pHrodo™ iFL dyes dramatically increase in fluorescence as the pH of their surroundings becomes more acidic, the antibodies coupled with the Zenon™ pHrodo™ iFL IgG Labeling Reagents provide an excellent measure of endocytic activity based on the acidification of the labeled antibodies as they are ingested by the cell.

The Zenon™ pHrodo™ iFL IgG Labeling Reagents contain sufficient material to label one to four 96-well plates, depending on the Zenon™ labeling reagent concentration used. Only a small amount of starting material is needed, and the method is optimized for efficient labeling of antibodies in serum, ascites fluid, or hybridoma suspensions.

Other advantages of the pH-sensitive Zenon™ pHrodo™ iFL IgG Labeling Reagents include:

  • Simplicity—No reagent purification is required
  • Accuracy—No wash steps or quenchers are needed, minimizing cross-reactivity or background
  • Speed—Labeled antibodies are typically ready to use in 10 minutes
  • Specificity—Dyes are designed for the specific detection of phagocytosis and endocytosis

Preserve primary antibody function and affinities

Reactive dye labeling of primary antibodies can have unpredictable and undesirable outcomes. One of these is reduced binding affinity due to label addition in the binding pocket. The Zenon™ antibody labeling approach, which is targeted to the Fc tail, resolves this potential issue.

Try custom antibody conjugates

If the antibody conjugate you need is not available as one of our stocked products, we will prepare a custom antibody conjugate for you. Our custom conjugation service is efficient and confidential, and we stand by the quality of our work. We are ISO 13485:2000 certified.

For Research Use Only. Not intended for animal or human therapeutic or diagnostic use.

For Research Use Only. Not for use in diagnostic procedures.
사양
색상Red
설명pHrodo™ iFL Red, 250 μL
여기/방출560/585 nm
키트 구성품1 vial of Zenon™ pHrodo™ iFL Red Human labeling reagent (250 μL)
라벨 유형pHrodo™ (pH sensitive)
제품라인Zenon™
제품 유형Labeling Reagent
수량250 μL
Human
Labeling TargetIgG
라벨 또는 염료pHrodo iFL Red
Unit Size250 μL
구성 및 보관
Store in refrigerator (2°C to 8°C) and protect from light
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문서 및 다운로드

Certificates | 증명서

Lot 번호Certificate TypeDateCatalog Number(s)
3249285Certificate of Analysis2025년 6월 20일Z25623
3224998Certificate of Analysis2025년 6월 17일Z25613
3192606Certificate of Analysis2025년 5월 13일Z25618
3159102Certificate of Analysis2025년 4월 13일Z25626
3159097Certificate of Analysis2025년 4월 13일Z25623
시험 성적서 관련 5 개의 결과가 검색되었습니다.

Safety Data Sheets | 물질 안전 보건 자료

인용 및 참조 문헌 (3)

인용 및 참조 문헌
Abstract
LILRA2 selectively modulates LPS-mediated cytokine production and inhibits phagocytosis by monocytes.
Authors:Lu HK, Mitchell A, Endoh Y, Hampartzoumian T, Huynh O, Borges L, Geczy C, Bryant K, Tedla N
Journal:PLoS One
PubMed ID:22479404
'The activating immunoglobulin-like receptor, subfamily A, member 2 (LILRA2) is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophages, neutrophils, basophils and eosinophils but not on lymphocytes and NK cells. LILRA2 cross-linking on monocytes induces pro-inflammatory cytokines while inhibiting dendritic cell differentiation and antigen presentation. ... More
High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1.
Authors:Opalinski L, Szymczyk J, Szczepara M, Kucinska M, Krowarsch D, Zakrzewska M, Otlewski J
Journal:Int J Mol Sci
PubMed ID:29748524
Fibroblast growth factor receptor 1 (FGFR1) is a plasma membrane protein that transmits signals from the extracellular environment, regulating cell homeostasis and function. Dysregulation of FGFR1 leads to the development of human cancers and noncancerous diseases. Numerous tumors overproduce FGFR1, making this receptor a perspective target for cancer therapies. Antibody-drug ... More
Novel Silyl Ether-Based Acid-Cleavable Antibody-MMAE Conjugates with Appropriate Stability and Efficacy.
Authors:Wang Y, Fan S, Xiao D, Xie F, Li W, Zhong W, Zhou X,
Journal:Cancers (Basel)
PubMed ID:31288450
Antibody-drug conjugate (ADC) is a novel efficient drug delivery system that has been successfully used in clinical practice, and it has become a research hotspot in the anti-tumor drug field. Acid-cleavable linkers were first used in clinical ADCs, but their structural variety (e.g., hydrazone and carbonate) is still limited, and ... More
3 total citations

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