IgE-mediated reactions
In general, feathers have been reported to cause allergic asthma and rhinitis and possibly also atopic dermatitis. In a study reporting sensitivity to feathers, bird serum, excrement, egg yolk, Hen´s egg-white and Chicken meat, it was found that sensitisation was acquired through the inhalation of bird components.
Laboratory tests found specific IgE to feathers, livetin, Hen´s egg-white and yolk in these patients.
Results from Kilpöe et al. suggest that true feather allergy is rare and that some of the positive reactions in skin-prick tests to feather extracts are probably caused by Mite allergens present in feathers (1).
Hypersensitivity lung disease has been reported in the Turkey raising industry (2).
This disease is also known as extrinsic allergic alveolitis, Bird Fancier's Lung and Farmer's Lungand is a disease of inflammation of the lung parenchyma in the terminal bronchioles and alveoli. Symptoms may start soon after exposure to bird allergens or after many years, and may include breathlessness, cough, occasional chills, and fever. Death may also result.
Clinical allergy to commercial feather products is less common than usually thought, as a result of the removal of dust, washing, and drying at 125oC. The allergens derived from unrefined feathers include bird serum proteins, bird droppings, and feather Mites (2).