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Whole Allergen

f236 Cow's whey

f236 Cow's whey Scientific Information

Type:

Whole Allergen

Display Name:

Cow's whey

Latin Name:

Bos taurus

Other Names:

Cow's whey

Route of Exposure

Main 

Processed cheese

Unexpected exposure

Bread and pastry, Ice cream, dry mixes, milk formulas for infants

Clinical Relevance

IgE-mediated reactions

Whey is milk depleted of most of the casein but otherwise equivalent to intact milk. a-lactalbumin and b-lactoglobulin are major allergens.

Milk proteins contain about 20% whey components. These are denatured in varying degrees by heating (1). a-lactalbumin, b-lactoglobulin and bovine serum albumin (BSA) are major allergens of whey.

Other topics

A study reported anaphylaxis after ingestion of a hydrolyzed whey protein formula in an infant. They urged caution when introducing such formulae to highly sensitive children.(2)

Compiled By

Last Reviewed : June 2022

References
  1. Kilshaw, PJ; Effects of heat treatment of cow’s milk and whey on the nutritional quality and antigenic properties. Arch Dis Child; 1982; 57: 842- 847.
  2. Ellis, MH; Short, J; Heiner, DC. Anaphylaxis after ingestion of a recently introduced hydrolyzed whey protein formula. J Pediatr; 1991; 118: 74-77.