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Pre-packed chromatography columns for bioprocess applications
Chromatography columns are critical to achieving successful separation of any biomolecule in downstream applications. Our pre-packed chromatography columns are designed to save time and money when used in your biotherapeutic purification workflow. We offer a variety of column sizes and formats, packed with Thermo Scientific chromatography resins. Our columns range in size from small volume RoboColumns, such as GoPure and MiniChrom™ columns used for process development, to bench scale.
No matter what your application is, we have a packed column ready when you are. Our pre-packed columns can help increase your productivity by:
- Offering a quick and easy set-up
- Allowing for increased process flexibility
- Helping create efficiencies so there is more time for more test runs
- Reducing labor time related to column packing and cleaning
Pre-packed chromatography columns for multiple applications
Our pre-packed columns come in a variety of formats, suitable for high throughput screening, process development, bench-scale screening, and small-scale preparative chromatography.
Column type |
RoboColumn™ |
GoPure small-scale prepacked column |
MiniChrom column |
Prepacked column |
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Application |
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Volume |
50 µL |
200 µL |
600 µL |
1 mL |
5 mL |
1 mL |
5 mL |
1 mL |
5 mL |
Diameter |
0.5 cm |
0.5 cm |
0.5 cm |
0.5 cm |
0.8 cm |
0.8 cm |
0.8 cm |
0.7 cm |
1.4 cm |
Bed height |
0.25 cm |
1 cm |
3 cm |
5 cm |
10 cm |
2 cm |
10 cm |
2.5 cm |
3.25 cm |
High throughput screening (Process development)
RoboColumns are small chromatography columns that are provided in 8-column strips. These columns are useful for fully automated and parallel chromatographic separations using a robotic liquid handling platform and are available in 50 µL, 200 µL, and 600 µL volumes.
Bench-scale process development screening
The GoPure and MiniChrom columns are designed for bench-scale resin screening, process development, and sample preparation. The 1 mL columns can be used for quick screenings of application feasibility and lab scale purification on a convenient and easy-to-use pre-packed column. The 10 cm bed height of the 5 mL columns allows initial process development on a bench scale.
Preparative chromatography
For your small-scale preparative chromatography needs, we have pre-packed our affinity resins into columns which can be used for simple and efficient protein purification in small volumes.
Find your column by resin type
Affinity
The CaptureSelect affinity chromatography technology offers a unique affinity purification solution based on single domain [VHH] antibody fragments. The affinity resins provide high target purity in a single step, independent of feedstock.
The affinity ligands are developed to meet all predefined requirements such as high specificity to the target molecule, mild elution during the purification process and high stability of the final resin. Manufacturing in an animal free production process allows for use in commercial purification processes
Ion exchange
POROS Ion Exchange Resins are designed for high-dynamic binding capacity over a range of pH and conductivity conditions, thereby increasing process development flexibility and manufacturing throughput.
POROS HS and XS resins are strong cation exchange resins based on a sulfopropyl functionalization, designed for the purification of more basic proteins and biomolecules. They are especially well suited for the separation of process impurities and aggregates.
Hydrophobic interaction
POROS HIC resins are available in a differentiating range of hydrophobicity, suitable for bind/elute and flow-through applications. The resins can be utilized at lower salt concentrations for the purification of a wide variety of biomolecules including therapeutic proteins, antibody fragments, antibody drug conjugates (ADCs), and other large molecules.
Chromatography Learning Lab
Check out the new Chromatography Learning Lab from Thermo Fisher Scientific, providing a robust range of webinars, articles, eBooks, infographics, and other digital resources to help you optimize the use of our purification products in your process.
Additional bioprocessing resources
As a trusted partner, we are committed to supporting your journey toward innovative biotech solutions.
