SNP Genotyping Workflow Solutions for Pharmacogenomics (PGx) Research

Over seven million samples analyzed to date—and growing

 

Combining the power of the QuantStudio 12K Flex Real-time PCR System with qualified TaqMan genotyping assays, this solution delivers a sample-to-answer workflow that allows you to introduce pharmacogenomic testing into your laboratory with ease.

Features and benefits

Our SNP genotyping workflow features:

  • Fully qualified content—All TaqMan SNP Genotyping Assays have been tested against genomic DNA and synthetic controls
  • Express Panels with our most popular PGx content, including—CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4, CYP3A5, SLCO1B1, VKORC1, COMT, OPRM1, DRD2, FII, FV, MTHFR, APOE2, APOE4
  • Flexible formats—Optimized for custom content to fit your needs, or off-the shelf content
  • Extensive menu of targets—Over 2,700 TaqMan SNP Genotyping Assays available, targeting the most common drug metabolizing enzyme (DME) markers (including CYP2D6, CYP2C9, CYP4F2, and more)
  • Calling and reporting solutions—TaqMan Genotyper Software and AlleleTyper Software are available* to quickly and easily determine haplotypes of samples using star-allele nomenclature
  • Utilizing familiar instruments—Compatible with QuantStudio 5 or QuantStudio 7 for custom plates, and QuantStudio 12K Flex System for OpenArray

*Additional PGx data and support files at bottom of page

Our SNP genotyping solutions are available in TaqMan OpenArray (OA) and Array Plate (TAP) formats.

  TaqMan OpenArray (OA) TaqMan Array Plates (TAP)
Focus

For mid-higher throughput applications

For low-mid throughput applications
Targets

TaqMan OpenArray PGx Express – 60:

  • 48 samples/plate
  • 60 pre-selected TaqMan PGx Assays

32 assays x 12 samples: 80 plates

64 assays x 6 samples: 160 plates

128 assays x 3 samples: 320 plates
Use cases
  • Customers interested in 48–120 markers
  • Genotyping of DME
  • Customers interested in 12–60 markers
  • Less waste
Format and approximate workflow timeline

Off-the-Shelf and Custom

2,880 reactions with pre-spotted assays

4-hour workflow

Off-the-Shelf and Custom

384-well plates with pre-spotted assays

PGx Express (60) on 384-well plates

3-hour workflow
Compatible instruments
  • QuantStudio 12K Flex Real-Time PCR System with OpenArray block
  • QuantStudio 12K Flex with 384-well block
  • QuantStudio 7 Flex & 7 Pro with 384-well block
  • QuantStudio 6 Flex & 6 Pro with 384-well block
  • QuantStudio 5 with 384-well block

Ordering information

SNP genotyping workflow

We offer a simple, efficient workflow designed to optimize your process and maximize your results.

For Research Use Only. Not for use in diagnostic procedures.