The plastic and glass surfaces of pipette tips and tubes including PCR tubes, microcentrifuge tubes, and conical tubes, are an easily overlooked source of ribonuclease (RNase) contamination. Thermo Fisher offers a range of RNase-free plastics including pipette tips, PCR tubes, microcentrifuge tubes, and conical tubes. Each lot of Invitrogen brand tips and tubes undergoes rigorous testing to ensure that they are nuclease-free (RNase- and DNase-free).

Basics of RNase control Working with RNA

RNase-free, nuclease-free tips and tubes

RNase-free, nuclease-free lab supplies are essential in lab spaces where researchers work with RNA. Common lab supplies such as pipette tips, PCR tubes, microcentrifuge tubes, and conical tubes are offered in an RNase-free format.

RNase-free pipette tips

Invitrogen RNase-free Tips, 200 μL size product photo

For safe transfer of samples and reagents, RNase-free pipette tips come in two different formats: without a barrier/filter and with a barrier/filter (also known as barrier tips or filter tips). Both formats have the following features:

  • E-beam sterilized—nuclease-free and RNase-free
  • Autoclave-safe
  • Compatible with a broad range of pipettors

Ordering information for RNase-free pipette tips

Catalog # Name Size Price (USD) Qty
AM12650 RNase-free Tips, 200 μL size 10 racks
181.00
AM12635 Barrier (Filter) Tips, 10 μL size (compatible with Eppendorf™ pipettors) 10 racks
259.65

Online Exclusive

267.00
Save 7.35 (3%)
AM12645 Barrier (Filter) Tips, 20 μL size 10 racks
257.65

Online Exclusive

265.00
Save 7.35 (3%)
AM12648 Barrier (Filter) Tips, 100 μL size 10 racks
260.00
AM12655 Barrier (Filter) Tips, 200 μL size 10 racks
261.00

RNase-free PCR tubes

nvitrogen PCR tubes with caps, RNase-free, 0.2 mL (8-strip format) product photo

RNase-free PCR tubes are available in different varieties. RNase-free PCR tubes offer thinner walls to allow for better sample temperature regulation, as well as frosted surfaces for easy labeling. Other options include domed or flat caps, as well as 0.2 mL and 0.5 mL formats. Thermo Fisher RNase-free PCR tubes have the following features:

  • Certified nuclease-free and RNase-free
  • Allow uniform contact with the thermal cycler temperature block
  • Autoclave-safe

Ordering information for RNase-free PCR tubes

Catalog # Name Size Price (USD) Qty
AM12225 Thin-walled, frosted lid, RNase-free PCR tubes (0.2 mL) Each
219.65

Online Exclusive

226.00
Save 6.35 (3%)
AM12230 PCR Tubes & Caps, RNase-free, 0.2 mL (8-strip format) Each
269.65

Online Exclusive

278.00
Save 8.35 (3%)
AM12250 Thin-walled, dome cap, RNase-free PCR tubes (0.5 mL) Each
174.00
AM12275 Thin-walled, frosted lid, RNase-free PCR tubes (0.5 mL) Each
181.65

Online Exclusive

187.00
Save 5.35 (3%)

RNase-free microcentrifuge tubes

Invitrogen Nonstick, RNase-free Microfuge Tubes, 0.5 mL product photo

RNase-free microcentrifuge tubes are available in three different sizes (0.5 mL, 1.5 mL, and 2.0 mL) and have marked gradations for convenience. Our microcentrifuge tubes are lot tested for contaminants, such as nucleases including RNases and DNases. All our RNase-free microcentrifuge tubes have the following features:

  • Certified nuclease-free and RNase-free
  • Non-stick, low-binding surface
  • Positive-seal design that prevents caps from opening in boiling water baths
  • Autoclave-safe

Ordering information for RNase-free microcentrifuge tubes

Catalog # Name Size Price (USD) Qty
AM12300 Nonstick, RNase-free Microfuge Tubes, 0.5 mL, 1000 Tubes Each
136.65

Online Exclusive

140.00
Save 3.35 (2%)
AM12350 Nonstick, RNase-free Microfuge Tubes, 0.5 mL, 500 Tubes Each
111.65

Online Exclusive

115.00
Save 3.35 (3%)
AM12400 RNase-free Microfuge Tubes, 1.5 mL, 500 Tubes Each
113.65

Online Exclusive

128.00
Save 14.35 (11%)
AM12425 RNase-free Microfuge Tubes, 2.0 mL, 500 Tubes Each
108.65

Online Exclusive

121.00
Save 12.35 (10%)
AM12475 Nonstick, RNase-free Microfuge Tubes, 2.0 mL, 250 Tubes Each
99.65

Online Exclusive

103.00
Save 3.35 (3%)

RNase-free conical tubes for safe storage of samples and reagents from RNases

RNase-free conical tubes are available in two different sizes (15 mL and 50 mL) and have printed writing space and volume marks for convenience. Our RNase-free conical tubes have the following features:

  • Certified nuclease-free and RNase-free tubes come racked and are pre-assembled with green screw tops
  • Tubes come racked and are pre-assembled with green screw tops
  • Autoclave-safe

Ordering information for RNase-free conical tubes

Catalog # Name Size Price (USD) Qty
AM12500 Conical Tubes (15 mL) (racked) Each
353.65

Online Exclusive

370.00
Save 16.35 (4%)
AM12501 Conical Tubes (50 mL) (racked) Each
204.65

Online Exclusive

213.00
Save 8.35 (4%)

RNase-free pipette tips

Invitrogen RNase-free Tips, 200 μL size product photo

For safe transfer of samples and reagents, RNase-free pipette tips come in two different formats: without a barrier/filter and with a barrier/filter (also known as barrier tips or filter tips). Both formats have the following features:

  • E-beam sterilized—nuclease-free and RNase-free
  • Autoclave-safe
  • Compatible with a broad range of pipettors

Ordering information for RNase-free pipette tips

Catalog # Name Size Price (USD) Qty
AM12650 RNase-free Tips, 200 μL size 10 racks
181.00
AM12635 Barrier (Filter) Tips, 10 μL size (compatible with Eppendorf™ pipettors) 10 racks
259.65

Online Exclusive

267.00
Save 7.35 (3%)
AM12645 Barrier (Filter) Tips, 20 μL size 10 racks
257.65

Online Exclusive

265.00
Save 7.35 (3%)
AM12648 Barrier (Filter) Tips, 100 μL size 10 racks
260.00
AM12655 Barrier (Filter) Tips, 200 μL size 10 racks
261.00

RNase-free PCR tubes

nvitrogen PCR tubes with caps, RNase-free, 0.2 mL (8-strip format) product photo

RNase-free PCR tubes are available in different varieties. RNase-free PCR tubes offer thinner walls to allow for better sample temperature regulation, as well as frosted surfaces for easy labeling. Other options include domed or flat caps, as well as 0.2 mL and 0.5 mL formats. Thermo Fisher RNase-free PCR tubes have the following features:

  • Certified nuclease-free and RNase-free
  • Allow uniform contact with the thermal cycler temperature block
  • Autoclave-safe

Ordering information for RNase-free PCR tubes

Catalog # Name Size Price (USD) Qty
AM12225 Thin-walled, frosted lid, RNase-free PCR tubes (0.2 mL) Each
219.65

Online Exclusive

226.00
Save 6.35 (3%)
AM12230 PCR Tubes & Caps, RNase-free, 0.2 mL (8-strip format) Each
269.65

Online Exclusive

278.00
Save 8.35 (3%)
AM12250 Thin-walled, dome cap, RNase-free PCR tubes (0.5 mL) Each
174.00
AM12275 Thin-walled, frosted lid, RNase-free PCR tubes (0.5 mL) Each
181.65

Online Exclusive

187.00
Save 5.35 (3%)

RNase-free microcentrifuge tubes

Invitrogen Nonstick, RNase-free Microfuge Tubes, 0.5 mL product photo

RNase-free microcentrifuge tubes are available in three different sizes (0.5 mL, 1.5 mL, and 2.0 mL) and have marked gradations for convenience. Our microcentrifuge tubes are lot tested for contaminants, such as nucleases including RNases and DNases. All our RNase-free microcentrifuge tubes have the following features:

  • Certified nuclease-free and RNase-free
  • Non-stick, low-binding surface
  • Positive-seal design that prevents caps from opening in boiling water baths
  • Autoclave-safe

Ordering information for RNase-free microcentrifuge tubes

Catalog # Name Size Price (USD) Qty
AM12300 Nonstick, RNase-free Microfuge Tubes, 0.5 mL, 1000 Tubes Each
136.65

Online Exclusive

140.00
Save 3.35 (2%)
AM12350 Nonstick, RNase-free Microfuge Tubes, 0.5 mL, 500 Tubes Each
111.65

Online Exclusive

115.00
Save 3.35 (3%)
AM12400 RNase-free Microfuge Tubes, 1.5 mL, 500 Tubes Each
113.65

Online Exclusive

128.00
Save 14.35 (11%)
AM12425 RNase-free Microfuge Tubes, 2.0 mL, 500 Tubes Each
108.65

Online Exclusive

121.00
Save 12.35 (10%)
AM12475 Nonstick, RNase-free Microfuge Tubes, 2.0 mL, 250 Tubes Each
99.65

Online Exclusive

103.00
Save 3.35 (3%)

RNase-free conical tubes for safe storage of samples and reagents from RNases

RNase-free conical tubes are available in two different sizes (15 mL and 50 mL) and have printed writing space and volume marks for convenience. Our RNase-free conical tubes have the following features:

  • Certified nuclease-free and RNase-free tubes come racked and are pre-assembled with green screw tops
  • Tubes come racked and are pre-assembled with green screw tops
  • Autoclave-safe

Ordering information for RNase-free conical tubes

Catalog # Name Size Price (USD) Qty
AM12500 Conical Tubes (15 mL) (racked) Each
353.65

Online Exclusive

370.00
Save 16.35 (4%)
AM12501 Conical Tubes (50 mL) (racked) Each
204.65

Online Exclusive

213.00
Save 8.35 (4%)

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