IgE-mediated reactions
Anecdotal evidence suggests that Broccoli can occasionally induce symptoms of food allergy in sensitised individuals; however, few studies have been reported to date.
A positive reaction to Broccoli in a skin test of a female patient has been reported (1). She experienced pain and swelling in the mouth and throat, plus breathing difficulties, after intake of coleslaw. The researchers concluded: “IgE sensitivity can occur to foods in the Brassica family not normally thought to cause allergic reactions in man. It is vital for the physician to consider these foods when evaluating patients for food allergy”.
Other reactions
Allergic and occupational contact dermatitis to Broccoli has been reported (2,3). A 56-year-old female nurse presented with a 3-year history of severe eczema and recurrent blisters of her palms, with the left being more severely affected than the right. She was patch tested with, among other substances, parts of fresh vegetables that she commonly used (Carrot, Parsnip, Potato, Broccoli, Onion, Tomato and Bean (unspecified)). There was a positive reaction to cobalt, Compositae mix and Broccoli at 48 and 96 hours. A usage test with Latex gloves, a skin prick test to commercial Latex solution, and a skin prick test to Broccoli were negative. The patient’s hand eczema improved remarkably on avoiding direct contact with Broccoli and other vegetables (2).
Maternal intake of Cabbage, Cauliflower, Broccoli, Cow’s milk, Onion, and Chocolate were significantly related to colic symptoms in exclusively breast-fed infants (4).