clear search
Search
Search Suggestions
Recent searches Clear History
Allergy & Autoimmune Disease
Allergy Solutions
ImmunoCAP Allergy Solutions
The gold standard in in-vitro allergy diagnostics with more than 500 whole allergens and allergen mixes.
Allergen Components
Food Allergies
Interpretation Guides
Respiratory Allergies
Product Catalog
Specific IgE tests
Autoimmunity Solutions
EliA Autoimmunity Solutions
A high specificity and high sensitivity portfolio of more than 50 clinically relevant tests for autoimmune diseases.
Rheumatoid Arthritis
Connective Tissue Diseases
Celiac Disease
Thyroid Diseases
Vasculitis and Goodpasture Syndrome
Antiphospholipid Syndrome
Pernicious Anemia
Inflammatory Bowel Disease
Liver Diseases
Product Catalog
Systems
Phadia Laboratory Systems
Fully automated and scalable instruments to optimize allergy and autoimmune workflow.
Phadia 250
Phadia 1000
Phadia 2500
Phadia 5000
Helios Automated IFA System
Phadia Prime
Additional Services
Product Catalog
Resources
Center for Knowledge
Training, education, and service material for autoimmune and allergy testing.
Allergen Encyclopedia
ImmunoCAST Podcast
ImmunoSpotlight
Lab Ordering Guide
Lab Training
Library
On-Demand Education
PiRL
Quick Draw Newsletter
Service & Support
Special Allergen Service
Thermo Fisher Scientific
visit thermofisher.com
Talk with Us

Whole Allergen

t41 White hickory

t41 White hickory Scientific Information

Type:

Whole Allergen

Display Name:

White hickory

Family:

Juglandaceae

Latin Name:

Carya tomentosa (syn. C. alba)

Other Names:

White Hickory, Mockernut hickory, Mockernut, Whiteheart hickory, Hognut, and Bullnut

Environmental Characteristics

Other Topics

White hickory, closely related to the Pecan (Hickory) tree (Carya pecan), is a member of the Juglandaceae (Walnut) family and is the most abundant of the Hickories. The Carya or Hickory genus comprises 17 species, of which 15 are found in the United States, 1 in Mexico and 1 in southern China. In the United States, Hickories are found principally in the eastern states and not in the Pacific states (1).

The Hickories are similar to the Walnut in that they are tall spreading trees with smooth gray bark and large deciduous pinnate leaves; but they generally have fewer leaflets than the Walnut does. The bark becomes rough or scaly on mature trees.

Clinical Relevance

Other Topics

Hayfever from Pecan is often described, especially in areas where it is cultivated (2). Because of the close family and genus relationship between White hickory and Pecan, results of studies on the latter may be applicable to the former.

The pollen of the other Hickories is also known to cause hayfever where the trees are abundant (3). Other species of Carya may be involved, e.g., the Shagbark (or Shellbark) hickory (C. ovata), Nutmeg hickory (C. myristicaeformis Nutt) and Pignut hickory (C. glabra) (2).

In a study of 371 allergy patients tested serologically for hypersensitivity to prevalent tree pollens in the area surrounding New York over the years 1993-2000, the highest prevalence of hypersensitivity was for Oak (34.3%), Birch (32.9%), and Maple (32.8%) tree pollens. Lower prevalences were observed for Beech (29.6%), Hickory (27.1%), Ash (26%), Elm (24.6%), and Poplar (20.6%) trees (4).

In an earlier study in St. Louis, Missouri, USA, a population was skin-tested with pollen from 12 wind-pollinated tree species. Pollen extracts of Box elder, Willow and Hickory elicited the strongest allergic reactions; Oak, Birch, Sycamore, Black walnut and Poplar more-moderate reactions; while allergens from Cottonwood, Maple, Elm and White ash were less reactive (5).

Sensitisation to the close genus member C. pecan has been demonstrated in Israel (6) and Mexico (7,8).

Molecular Aspects

No allergens have been characterised.

Cross Reactivity

Cross-reactivity could be expected between species of the genus Juglans and of the genus Carya, e.g., White hickory and Pecan tree.

Compiled By

Last reviewed: May 2022

References
  1. Wodehouse RP. Hayfever Plants. 2nd revised edition. Hafner Publishing Co., NY, USA. 1971
  2. Weber RW. Pecan. Ann Allergy Asthma Immunol 2004;93(3):A-6
  3. Brown GT. Seasonal hayfever with special reference to the Middle Altantic states. J Med Soc N J. 1932;29:483-90
  4. Lin RY, Clauss AE, Bennett ES. Hypersensitivity to common tree pollens in New York City patients. Allergy Asthma Proc 2002;23(4):253-8
  5. Lewis WH, Imber WE Allergy epidemiology in the St. Louis, Missouri, area. III. Trees. Ann Allergy 1975;35(2):113-9
  6. Rachmiel M, Waisel Y, Verliger H, Keynan N, Katz Y. Correlation between exposure to allergenic pollens and allergic manifestations. [Hebrew] Harefuah 1996;130(8):505-11, 584
  7. Ramos Morin CJ, Canseco Gonzalez C. Hypersensitivity to airborne allergens common in the central region of Coahuila. [Spanish] Rev Alerg Mex 1994;41(3):84-7
  8. Ramos Morin CJ, Canseco Gonzalez C Hypersensitivity to common allergens in the central region of Coahuila [Spanish]. Rev Alerg Mex 1993;40(6):150-4