Drug Screening and Confirmation Products

Drug toxicology instruments and consumables

No matter what the size of your lab or complexity of your toxicology testing needs, we have the instruments and supplies—backed by service and support—to meet your needs and budget. From reliable chemistry analyzers and assays to technologically advanced, all-in-one LC-MS/MS systems, we have you covered.

Quantitation of 106 drugs in urine by LC-MS

Access poster on 7-minute method to quantitate 106 drugs in urine

Sample preparation and consumables

Confidence in your test results begins with meticulous sample preparation and choosing the correct consumables for your chromatography and mass spectrometry instrument and application.

Thermo Scientific SOLA Cartridges and Plates

SOLA and SOLAµ products are designed for bioanalytical and clinical research analysts who are tasked with providing robust, sensitive, and highly reproducible results from complex biological samples in a high-throughput environment.

 

SOLA and SOLAµ sample prep products for complex biological samples

Thermo Scientific SureSTART Collection

For LCMS sample vials and plates, we offer a wide range of volumes/depths, snap or screw tops, and made of many materials to best fit your application needs.

 

SureSTART sample vial and plate collection

Chemical analyzer screening

Presumptive drug screening on urine specimens may be performed using immunoassay analyzers. Urine drug tests are frequently used in the criminal justice system, for workplace testing, and by pain management clinics. For situations with lower sample throughput needs, immunoassay analyzers are a budget-friendly, simple testing method that doesn’t require highly trained experts to run the tests and analyze the results. Samples testing positive are sent for confirmation by LC-MS.

 

Automated drug testing integrates all steps involved in monitoring for drug use—from scheduling a test, tracking chain of custody, barcoding specimens, testing the specimen for drugs, to reporting test results electronically.

Thermo Scientific Indiko Clinical Chemistry Analyzer

  • Rapidly screen urine
  • Easy to use for new analysts
  • Process 200 samples per hour
  • Fully automated
  • Methods traceable to international reference methods and materials
  • Large menu of assay kits and controls
Indiko Clinical Chemistry Analyzer

Thermo Scientific Indiko Plus Clinical Chemistry Analyzer

  • Rapidly screen urine—first results in 15 minutes
  • Easy to use for new analysts
  • Process 350 samples per hour
  • Fully automated
  • Methods traceable to international reference methods and materials
  • Large menu of assay kits and controls
Indiko Plus Clinical Chemistry Analyzer

Learn more about immunoassay drug screening solutions

Learn more about immunoassay drug screening solutions

Liquid chromatography separation

For confirmatory testing or even screening for some labs, liquid chromatography (LC) is required to separate drugs of abuse before the ions enter the detector. Depending on your lab's throughput or assay needs, we have varying LC systems that may decrease run-time or sample preparation costs. For labs with routine, lower sample throughput, a single-channel LC system is sufficient. If your lab is testing hundreds or thousands of samples, a multi-channel LC system will help maximize testing efficiency.


Thermo Scientific Vanquish Flex UHPLC and
Vanquish Horizon UHPLC Systems


Thermo Scientific Transcend VLX-2 UHPLC System


Thermo Scientific Transcend TLX UHPLC System
  • Single channel
  • Small lab footprint
  • Multi-channel
  • Small lab footprint
  • Ability to run the same or different methods on each of the 2 channels
  • Multi-channel
  • 2 or 4 channel enables ability to run the same or different methods on each channel
  • Ability for online Turboflow

LC column selection guide

For clinical and forensic toxicology labs, robustness and detection limits are of the upmost importance. That is why we provide a diverse selection of columns to cater to your specific workflow requirements.


Thermo Scientific Hypersil GOLD Columns


Thermo Scientific Accucore Columns


Thermo Scientific Acclaim Columns
  • Fully porous, ultrapure silica particle columns
  • Built on 40 years of experience in column development and manufacturing
  • Excellent resolution, efficiency, and sensitivity for routine, high-quality separations
  • Fully scalable from UHPLC to prep
  • Solid core silica technology columns
  • UHPLC efficiency on any instrument
  • Rapid, high-resolution separation of complex samples and limited sample volumes
  • Increased sensitivity and peak capacity using standard HPLC
  • Fully porous, highly retentive silica particle columns
  • Ideal for complex mixtures that require higher resolution
  • Wide variety of column chemistries with various selectivities, including mixed-mode and HILIC

PaperSpray direct ionization

An alternative solution to using LC-MS for qualitative and quantitative analysis of drugs is paper spray ionization. This technique provides direct sample analysis capability with your triple quadrupole mass spectrometer, eliminating the need for chromatographic based separation, simplifying your workflow, getting to results faster, and reducing cost per test. This technique minimizes solvent consumption and time-consuming sample preparation steps like derivatization, while avoiding needs for expert operators and instrument downtime.

Thermo Scientific VeriSpray PaperSpray Ion Source

  • Obtain screening results in under 2 minutes per sample
  • Eliminate sample prep or extraction
  • Run 240 samples without user intervention
  • Reduce solvent usage
VeriSpray PaperSpray Ion Source

Mass spectrometry analysis

Screen, confirm, and identify known and unknowns

Confirmation, which is performed by a mass spectrometer, is used to identify and quantitate the analytes of interest often following drug screening. From analysis with a targeted panel to finding the unknowns in a sample using an untargeted assay, we can help match you with a solution to meet your testing needs.

Thermo Scientific TSQ Quantis Plus Triple Quadrupole Mass Spectrometer

  • Increased sensitivity and performance deliver confident method development and precise quantitation for high-throughput applications
  • Enhanced collision cell improves transmission of low mass product ions for increased sensitivity
  • Ultra-fast screening with acquisition rate of 600 SRMs/sec and 5 ms polarity switching
TSQ Quantis Plus Triple Quadrupole Mass Spectrometer

Thermo Scientific Orbitrap Exploris 120 Mass Spectrometer

  • Accelerate qualitative and quantitative confidence with consistently accurate data for targeted and untargeted analysis
  • High resolution instrumentation to distinguish between interferences/isobars
  • Retrospective analysis to find novel psychoactive substances as the emerge
  • Resolution up to 120,000 (FWHM) at m/z 200 with scan speeds up to 22 Hz
Orbitrap Exploris 120 Mass Spectrometer

Thermo Scientific Stellar Mass Spectrometer

  • Expanded scale, higher sensitivity, greater specificity, increased throughput for exceptional productivity
  • Adaptive RT routine performs dynamic RT adjustments to overcome minor LC shifts
  • HCD and CID fragmentation ability and 5 ms polarity switching
  • Scan rates for MS2 and MS3 of 124 and 40 Hz, respectively
Stellar Mass Spectrometer

For Research Use Only. Not for use in diagnostic procedures.