Isolectin GS-IB4 From Griffonia simplicifolia, Alexa Fluor™ 568 Conjugate
Isolectin GS-IB<sub>4</sub> From <i>Griffonia simplicifolia</i>, Alexa Fluor&trade; 568 Conjugate
Invitrogen™

Isolectin GS-IB4 From Griffonia simplicifolia, Alexa Fluor™ 568 Conjugate

Isolectin GS-IB4 is a 114,000-dalton glycoprotein that is part of a family of five tetrameric type I isolectins (IA4, IA3B,Read more
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Catalog NumberQuantity
I21412500 μg
Catalog number I21412
Price (EUR)
798,00
Each
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Quantity:
500 μg
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Price (EUR)
798,00
Each
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Isolectin GS-IB4 is a 114,000-dalton glycoprotein that is part of a family of five tetrameric type I isolectins (IA4, IA3B, IA2B2, IAB3, and IB4) isolated from the seeds of the tropical African legume Griffonia simplicifolia. The A subunit prefers N-acetyl-D-galactosamine end groups while the B subunit is selective for terminal a-D-galactosyl residues. The red fluorescent Alexa Fluor™ 568 isolectin GS-IB4 conjugate can be used in fluorescence microscopy.

View complete list of fluorescent dye-conjugated lectins ›
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Quantity500 μg
SourceAfrica Shrub legume
ConjugateAlexa Fluor 568
Label TypeAlexa Fluor Dyes
Shipping ConditionRoom Temperature
FormLyophilized
Protein SubtypeLectins
Product LineAlexa Fluor™
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
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Fluorescence spectra

Fluorescence spectra

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Certificates

Lot #Certificate TypeDateCatalog Number(s)
2831365Certificate of AnalysisJan 31, 2024I21412
2551335Certificate of AnalysisFeb 02, 2023I21412
2591218Certificate of AnalysisJan 27, 2023I21412
2373256Certificate of AnalysisOct 18, 2021I21412
2260918Certificate of AnalysisNov 18, 2020I21412
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Factors to consider are size of tracer, method of delivery (injection, direct application to tissue, etc.), and if the tracer needs to be fixable. Here are some links to details about the various classes of neuronal tracers we offer and how to choose between them:

Neuronal Tracing (https://www.thermofisher.com/us/en/home/life-science/cell-analysis/cell-tracing-tracking-and-morphology/neuronal-tracing.html)
Choosing a Tracer (https://www.thermofisher.com/us/en/home/references/molecular-probes-the-handbook/fluorescent-tracers-of-cell-morphology-and-fluid-flow/choosing-a-tracer.html)
Imaging Analysis (http://assets.thermofisher.com/TFS-Assets/BID/Reference-Materials/bioprobes-50-journal.pdf)

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Citations & References (31)

Citations & References
Abstract
Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons.
Authors:Takashima Y, Daniels RL, Knowlton W, Teng J, Liman ER, McKemy DD,
Journal:J Neurosci
PubMed ID:18094254
'Sensory nerves detect an extensive array of somatosensory stimuli, including environmental temperatures. Despite activating only a small cohort of sensory neurons, cold temperatures generate a variety of distinct sensations that range from pleasantly cool to painfully aching, prickling, and burning. Psychophysical and functional data show that cold responses are mediated ... More
Antiangiogenic activity of 2-deoxy-D-glucose.
Authors:Merchan JR, Kovács K, Railsback JW, Kurtoglu M, Jing Y, Piña Y, Gao N, Murray TG, Lehrman MA, Lampidis TJ,
Journal:PLoS One
PubMed ID:21060881
'During tumor angiogenesis, endothelial cells (ECs) are engaged in a number of energy consuming biological processes, such as proliferation, migration, and capillary formation. Since glucose uptake and metabolism are increased to meet this energy need, the effects of the glycolytic inhibitor 2-deoxy-D-glucose (2-DG) on in vitro and in vivo angiogenesis ... More
Early activation, motility, and homing of neonatal microglia to injured neurons does not require protein synthesis.
Authors:Kurpius D, Wilson N, Fuller L, Hoffman A, Dailey ME
Journal:Glia
PubMed ID:16715500
'Neuronal injury in CNS tissues induces a rapid activation and mobilization of resident microglia (MG). It is widely assumed that changes in gene expression drive the morphological transformation of MG and regulate their mobilization during activation. Here, we used acutely excised neonatal rat brain slices to test whether the morphological ... More
A sensory-labeled line for cold: TRPM8-expressing sensory neurons define the cellular basis for cold, cold pain, and cooling-mediated analgesia.
Authors:Knowlton WM, Palkar R, Lippoldt EK, McCoy DD, Baluch F, Chen J, McKemy DD,
Journal:J Neurosci
PubMed ID:23407943
'Many primary sensory neurons are polymodal, responding to multiple stimulus modalities (chemical, thermal, or mechanical), yet each modality is recognized differently. Although polymodality implies that stimulus encoding occurs in higher centers, such as the spinal cord or brain, recent sensory neuron ablation studies find that behavioral responses to different modalities ... More
Exercise training prevents skeletal muscle afferent sensitization in rats with chronic heart failure.
Authors:Wang HJ, Li YL, Zucker IH, Wang W,
Journal:Am J Physiol Regul Integr Comp Physiol
PubMed ID:22496362
An exaggerated exercise pressor reflex (EPR) contributes to exercise intolerance and excessive sympathoexcitation in the chronic heart failure (CHF) state, which is prevented by exercise training (ExT) at an early stage in the development of CHF. We hypothesized that ExT has a beneficial effect on the exaggerated EPR by improving ... More
31 total citations

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