Fetal Bovine Serum (FBS), Premium
Fetal Bovine Serum (FBS), Premium
Fetal Bovine Serum (FBS), Premium
Fetal Bovine Serum (FBS), Premium
Fetal Bovine Serum (FBS), Premium
Gibco™

Fetal Bovine Serum (FBS), Premium

Green features
Gibco fetal bovine sera offer excellent value for basic cell culture, specialty research, and specific assays, earning the trust of researchers with consistent quality and award-winning support that helps meet your research needs and budget requirements.
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Catalog NumberQuantityFormatHeat InactivatedGamma-irradiated
A567050150 mLOne ShotYesNo
A567040150 mLOne ShotNoNo
A567040210 x 50 mLOne ShotNoNo
A567050210 x 50 mLOne ShotYesNo
A5670701500 mLBottleNoNo
A5670801500 mLBottleYesNo
A5670901500 mLBottleNoYes
A5670201500 mLBottleYesYes
Catalog number A5670501
Price (EUR)
97,25
Each
-
Add to cart
Quantity:
50 mL
Format:
One Shot
Heat Inactivated:
Yes
Gamma-irradiated:
No
Recurring order eligible. Learn more »
Price (EUR)
97,25
Each
Add to cart
Ask our AI about this Product

Gibco fetal bovine sera offer excellent value for basic cell culture, specialty research, and specific assays, earning the trust of researchers with consistent quality and award-winning support that helps meet your research needs and budget requirements.

Sera category: Premium

  • Use for general cell culture with common cell lines
  • Low endotoxin and hemoglobin levels
  • Endotoxin level: <10 EU/mL
  • Hemoglobin level: <25 mg/dL
  • Origin: refer to CoA for specific origin. All products may not be available in all regions due to importation regulations.
  • US Department of Agriculture (USDA) safety tested for the absence of bluetongue and akabane from countries that are USDA-approved for importation into the US

Gibco serum delivers

  • ISO 13485–certified; processed in FDA registered facilities
  • Triple-filtered at 0.1 μm
  • Gibco bottle easier to use in hood; helps reduce risk of contamination and improve consistency
  • Peel-off sticker on label provides handy reference for lot number and expiration date recording in lab notebook
For research use or further manufacturing use only. Serum and blood proteins are not for direct administration into humans or animals.
Specifications
Endotoxin Concentration≤10 EU/mL
Gamma-irradiatedNo
GradePremium
Green FeaturesLess waste
Heat InactivatedYes
Hemoglobin Concentration≤25 mg/dL
Purity or Quality GradePremium
Shelf Life5 Years
Shipping ConditionDry Ice
SpeciesCattle/Bovine
Tested ForUp to 60 quality tests including 9CFR virus testing, endotoxin, and performance
AgeFetal
Country of OriginRefer to CoA for specific origin
FormFrozen
FormatOne Shot
Product TypeFetal Bovine Serum
Quantity50 mL
Serum TreatmentHeat-inactivated
SterilitySterile-filtered
Sterilization MethodTriple-filtered, 0.1 μm
Unit SizeEach
Contents & Storage
Store at ≤-10°C.
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Certificates

Lot #Certificate TypeDateCatalog Number(s)
U3225692RPCertificate of AnalysisJun 25, 2025A5670501, A5670502
U3225685RPCertificate of AnalysisJun 25, 2025A5670401, A5670402
U3225685RPCertificate of AnalysisJun 25, 2025A5670701
U3231058RPCertificate of AnalysisJun 15, 2025A5670801
U3225681RPCertificate of AnalysisJun 12, 2025A5670501, A5670502
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Safety Data Sheets

Frequently asked questions (FAQs)

  1. Heating inactivates complement. Active complement can participate in cytolytic events, contract smooth muscle, release histamine from mast cells and platelets, and activate lymphocytic and macrophage cells. Applications where heat-inactivated serum is recommended include immunological studies and culturing of embryonic stem cells (ESCs), insect cells, and smooth muscle cells.
  2. Heat inactivation helps to achieve bottle-to-bottle and lot-to-lot stability by neutralizing many factors that can vary largely from lot to lot.
  3. There aren't necessarily disadvantages to heat inactivation of FBS, but there is some evidence that suggests there may be no added benefit to it unless you are carrying out immune studies.

Note: Heat inactivation is performed in a 56 degrees C water bath for 30 min with swirling every 10 min or so for heat distribution and to lower the degree of protein aggregation/flocculant precipitation. Note: If the time or temperature is exceeded, the serum may thicken to a gel. If this occurs, the serum is no longer usable. Unnecessary heat inactivation can take up time and potentially lead to wasted reagents if a mistake is made during the protocol1.

1. Pellerin, et al., Bioengineering, published in 2021.

Find additional tips, troubleshooting help, and resources within our Mammalian Cell Culture Basics Support Center.

Our CoAs only capture the total protein content not specifically the amount attributed to albumin.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

FBS is added to culture medium at a concentration of 2-10% to provide attachment factors, nutrients, and hormones for mammalian cells, as well as to be a buffer against disruptions like pH changes and endotoxins. FBS has significant amounts of embryonic growth promoting factors like hormones, carrier proteins, and macromolecular proteins. It also has low levels of antibodies and other growth-inhibiting components. For most basal medium, 10% FBS is used. Some applications require up to 20% supplementation, so researchers need to determine what is optimal for their specific application and cell line.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

This product can be stored at 4 degrees C for up to 4 weeks. Once the medium has been supplemented with serum, we recommend using it within 2-4 weeks.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

We recommend thawing the serum overnight at 4 degrees C or in a 37 degrees C water bath, removing as soon as it is thawed. Once thawed, aliquot into single-use sizes and freeze the aliquots. Each aliquot should ideally be thawed only one additional time as repeated freeze-thaw cycles are not recommended.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

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