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Citations & References (9)
Gibco™
Sodium Pyruvate (100 mM)
Sodium pyruvate is commonly added to cell culture media as a carbon source in addition to glucose. Since cells makeRead more
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| Catalog Number | Quantity |
|---|---|
| 11360070 | 100 mL |
Catalog number 11360070
Price (USD)
16.72
Each
In stock
Quantity:
100 mL
Price (USD)
16.72
Each
Sodium pyruvate is commonly added to cell culture media as a carbon source in addition to glucose. Since cells make sodium pyruvate as an intermediate metabolite in the glycolysis pathway, it is not a required supplement for all cell cultures. However, if cells have been grown in medium that is supplemented with sodium pyruvate, we recommend continuing use of the supplement as cell growth may lag without it. Gibco Sodium Pyruvate (100 mM) is formulated using 11 g per liter of water. The final concentration of sodium pyruvate used in most cell culture media is 1 mM.
cGMP Manufacturing and Quality System
For supply chain continuity, we manufacture Gibco Sodium Pyruvate (100 mM) at two separate facilities located in Grand Island, NY and Scotland, UK. Both sites are compliant with cGMP manufacturing requirements and are certified to the ISO 13485 standard.
cGMP Manufacturing and Quality System
For supply chain continuity, we manufacture Gibco Sodium Pyruvate (100 mM) at two separate facilities located in Grand Island, NY and Scotland, UK. Both sites are compliant with cGMP manufacturing requirements and are certified to the ISO 13485 standard.
For In Vitro Diagnostic Use.
Specifications
Cell TypeMammalian Cells
Concentration100 mM
Quantity100 mL
Shelf Life12 Months
Shipping ConditionRoom Temperature
FormLiquid
Product TypeSodium Pyruvate
SterilitySterile-filtered
Unit SizeEach
Contents & Storage
Storage conditions: 2°C to 8°C. Protect from light.
Shipping conditions: Room temperature
Shelf life: 12 months from date of manufacture
Shipping conditions: Room temperature
Shelf life: 12 months from date of manufacture
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Lot #Certificate TypeDateCatalog Number(s)
3224742Certificate of AnalysisJun 21, 202511360039, 11360070
3180897Certificate of AnalysisJun 04, 202511360039, 11360070
3126861Certificate of AnalysisMay 10, 202511360039, 11360070
3150446Certificate of AnalysisMay 03, 202511360039, 11360070
3144878Certificate of AnalysisFeb 13, 202511360039, 11360070
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Frequently asked questions (FAQs)
When stored properly at 2-8 degrees C, the product is stable for 12 months from date of shipment
Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.
Sodium pyruvate (Cat. No. 11360070) is supplied as a liquid supplement for cell culture media at 100 mM (100X) and a final concentration of 11,004 mg/L.
Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.
Sodium pyruvate serves as an additional energy source for cells in culture. It is often added to low-glucose formulations (1.0 g/L glucose) and is sometimes added to higher-glucose formulations as well. Cells can become “hooked” on sodium pyruvate however, and if it is withdrawn suddenly from the media, they may experience a short lag in growth.
Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.
Citations & References (9)
Search citations by name, author, journal title or abstract text
Citations & References
Abstract
A comparison between different human hepatocyte models reveals profound differences in net glucose production, lipid composition and metabolism in vitro.
Journal:Experimental cell research
PubMed ID:38499143
Effects of an indole derivative on cell proliferation, transfection, and alternative splicing in production of lentiviral vectors by transient co-transfection.
Journal:PloS one
PubMed ID:38833479
Lentiviral vectors derived from human immunodeficiency virus type I are widely used to deliver functional gene copies to mammalian cells for research and gene therapies. Post-transcriptional splicing of lentiviral vector transgene in transduced host and transfected producer cells presents barriers to widespread application of lentiviral vector-based therapies. The present study
Metabolism of 4 beta -hydroxycholesterol in humans.
Journal:J Biol Chem
PubMed ID:12077124
'One of the major oxysterols in the human circulation is 4 beta-hydroxycholesterol formed from cholesterol by the drug-metabolizing enzyme cytochrome P450 3A4. Deuterium-labeled 4 beta-hydroxycholesterol was injected into two healthy volunteers, and the apparent half-life was found to be 64 and 60 h, respectively. We have determined earlier the half-lives
Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O.
Journal:Proc Natl Acad Sci U S A
PubMed ID:11248053
'The pore-forming toxin streptolysin O (SLO) can be used to reversibly permeabilize adherent and nonadherent cells, allowing delivery of molecules with up to 100 kDa mass to the cytosol. Using FITC-labeled albumin, 10(5)-10(6) molecules were estimated to be entrapped per cell. Repair of toxin lesions depended on Ca(2+)-calmodulin and on
Use of human tissue explants to study human infectious agents.
Journal:Nat Protoc
PubMed ID:19197269
The study of human cell-cell and cell-pathogen interactions that occur in the context of complex tissue cytoarchitecture is critical for deciphering the mechanisms of many normal and pathogenic processes. This protocol describes methods for culturing and infecting explants of human tissues to study the pathogenesis of human infectious agents and
9 total citations