Diagram of Grignard reactions

Organomagnesium halides of the general structure R-Mg-X, with R = alkyl, alkenyl or aryl and X = halogen, are called “Grignard” reagents after their inventor, chemist Victor Grignard. Grignard reagents are highly reactive and react with most organic compounds. It also reacts with water, carbon dioxide, and oxygen. Grignard reagents are prepared by the reaction of magnesium metal with appropriate alkyl halide in ether solvent. The halogen may be chlorine, bromine, or iodine. A related synthesis uses ethylene oxide to prepare alcohols containing two more carbon atoms than that of the alkyl halide. Perhaps the most important use of the Grignard reagent is the reaction with aldehydes and ketones to form alcohols.

Thermo Fisher Scientific offers a range of Grignard reagents and related products in a variety of formats, including custom and bulk quantities.

Watch our video on the Grignard Reaction


Review available Thermo Scientific products for the Grignard reaction

Catalog # Name Price (USD) Qty
H51159.AD 1-Naphthylmagnesium bromide, 0.5M in MeTHF, Thermo Scientific Chemicals
260.00
H51159.AE 1-Naphthylmagnesium bromide, 0.5M in MeTHF, Thermo Scientific Chemicals
414.00
H54282.AE 2,4,6-Trimethylphenylmagnesium bromide, 1M in 2-MeTHF, Thermo Scientific Chemicals
385.00
H54159.AE 2,4-Dichlorobenzylmagnesium chloride, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
316.65

Online exclusive

352.00
Save 35.35 (10%)
H54966.AE 2,4-Difluorobenzylmagnesium bromide, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
305.65

Special offer

Online exclusive

Ends: 30-Jun-2025

359.00
Save 53.35 (15%)
H54337.AE 2,5-Dimethoxyphenylmagnesium bromide, 0.5M in 2-MeTHF, Thermo Scientific Chemicals
248.65

Online exclusive

276.00
Save 27.35 (10%)
H54189.AE 2,6-Difluorobenzylmagnesium bromide, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
233.65

Online exclusive

259.00
Save 25.35 (10%)
H54138.AE 2,6-Dimethylphenylmagnesium bromide, 0.5M in 2-MeTHF, Thermo Scientific Chemicals
133.00
H51171.AE 2-Butenylmagnesium chloride, 0.5M in MeTHF, Thermo Scientific Chemicals
222.65

Special offer

Online exclusive

Ends: 26-Sep-2025

262.00
Save 39.35 (15%)
H54820.AE 2-Chlorobenzylmagnesium chloride, 0.50M in 2-MeTHF, Thermo Scientific Chemicals
281.00
H54881.AE 2-Fluorobenzylmagnesium chloride, 0.50M in 2-MeTHF, Thermo Scientific Chemicals
Contact Us ›
-
H54177.AE 2-Methoxybenzylmagnesium chloride, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
536.65

Online exclusive

596.00
Save 59.35 (10%)
H54133.AE 3,4-Dichlorobenzylmagnesium chloride, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
Contact Us ›
-
H54312.AE 3,4-Difluorobenzylmagnesium bromide, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
246.65

Online exclusive

274.00
Save 27.35 (10%)
H54197.AE 3,4-Difluorophenylmagnesium bromide, 0.50 M in 2-MeTHF, Thermo Scientific Chemicals
258.00
H54654.AE 3,4-Dimethoxyphenylmagnesium bromide, 0.5M in THF, Thermo Scientific Chemicals
250.65

Special offer

Online exclusive

Ends: 26-Sep-2025

295.00
Save 44.35 (15%)
H54632.AE 3,4-(Methylenedioxy)phenylmagnesium bromide, 0.50 M in 2-MeTHF, Thermo Scientific Chemicals
242.00
H54427.AE 3,5-Difluorobenzylmagnesium bromide, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
204.65

Special offer

Online exclusive

Ends: 26-Sep-2025

241.00
Save 36.35 (15%)
H54622.AE 3,5-Difluorophenylmagnesium bromide, 0.50M in 2-MeTHF, Thermo Scientific Chemicals
231.00
H54781.AE 3,5-Dimethyl-4-methoxyphenylmagnesium bromide, 0.5M in 2-MeTHF, Thermo Scientific Chemicals
Contact Us ›
-
H54057.AE 3,5-Dimethylphenylmagnesium bromide, 0.5M in 2-MeTHF, Thermo Scientific Chemicals
446.65

Online exclusive

496.00
Save 49.35 (10%)
H54075.AE 3-Chloro-4-methylphenylmagnesium bromide, 0.50 M in 2-MeTHF, Thermo Scientific Chemicals
185.65

Special offer

Online exclusive

Ends: 30-Jun-2025

218.00
Save 32.35 (15%)
H54237.AE 3-Chlorobenzylmagnesium chloride, 0.50M in 2-MeTHF, Thermo Scientific Chemicals
296.65

Special offer

Online exclusive

Ends: 30-Jun-2025

349.00
Save 52.35 (15%)
H51161.AD 3-Chlorophenylmagnesium bromide, 1M in MeTHF, Thermo Scientific Chemicals
226.65

Online exclusive

252.00
Save 25.35 (10%)
H51161.AE 3-Chlorophenylmagnesium bromide, 1M in MeTHF, Thermo Scientific Chemicals
374.65

Special offer

Online exclusive

Ends: 30-Jun-2025

441.00
Save 66.35 (15%)
H54335.AE 3-Methoxybenzylmagnesium chloride, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
Contact Us ›
-
H54780.AE 3-Methoxyphenylmagnesium bromide, 1.0 M in 2-MeTHF, Thermo Scientific Chemicals
148.00
H54115.AE 4-(2-Tetrahydropyranyloxy)phenylmagnesium bromide, 0.5M in 2-MeTHF, Thermo Scientific Chemicals
422.65

Online exclusive

469.00
Save 46.35 (10%)
H54625.AE 4-Chlorobenzylmagnesium chloride, 0.50M in 2-Me-THF, Thermo Scientific Chemicals
Contact Us ›
-
H51163.AE 4-Chlorophenylmagnesium bromide, 1M in MeTHF, Thermo Scientific Chemicals
64.65

Online exclusive

71.80
Save 7.15 (10%)
H54865.AE 4-Fluoro-2-methylphenylmagnesium bromide, 0.50 M in 2-MeTHF, Thermo Scientific Chemicals
231.65

Special offer

Online exclusive

Ends: 30-Jun-2025

272.00
Save 40.35 (15%)
H54201.AE 4-Isobutylphenylmagnesium bromide, 0.5M in 2-MeTHF, Thermo Scientific Chemicals
213.65

Special offer

Online exclusive

Ends: 30-Jun-2025

251.00
Save 37.35 (15%)
H54078.AE 4-Methoxybenzylmagnesium chloride, 0.25M in 2-MeTHF, Thermo Scientific Chemicals
350.65

Special offer

Online exclusive

Ends: 30-Jun-2025

412.00
Save 61.35 (15%)
089435.AE 4-Methoxyphenylmagnesium bromide, 0.5M in THF, Thermo Scientific Chemicals
79.65

Special offer

Online exclusive

Ends: 30-Jun-2025

94.10
Save 14.45 (15%)
089435.AP 4-Methoxyphenylmagnesium bromide, 0.5M in THF, Thermo Scientific Chemicals
309.00
H54317.AE 4-Methoxyphenylmagnesium bromide, 1.0 M in 2-MeTHF, Thermo Scientific Chemicals
143.65

Online exclusive

159.00
Save 15.35 (10%)
H54411.AE 4-Phenoxyphenylmagnesium bromide, 0.5 M in 2-MeTHF, Thermo Scientific Chemicals
Contact Us ›
-
H54284.AE 4-tert-Butylphenylmagnesium bromide, 0.50 M in 2-MeTHF, Thermo Scientific Chemicals
286.65

Special offer

Online exclusive

Ends: 30-Jun-2025

337.00
Save 50.35 (15%)
H54501.AE 5-Chloro-2-methoxyphenylmagnesium bromide, 0.50M in 2-MeTHF, Thermo Scientific Chemicals
212.65

Special offer

Online exclusive

Ends: 26-Sep-2025

250.00
Save 37.35 (15%)
H51170.AE Allylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
130.00
H51170.AP Allylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
449.65

Special offer

Online exclusive

Ends: 30-Jun-2025

529.00
Save 79.35 (15%)
087299.AD Benzylmagnesium chloride, 1-2M in THF, Thermo Scientific Chemicals
83.30
H51154.AE Benzylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
253.65

Online exclusive

282.00
Save 28.35 (10%)
H51154.AP Benzylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
946.00
H51165.AE Cyclohexylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
55.60
H51165.AP Cyclohexylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
186.65

Special offer

Online exclusive

Ends: 30-Jun-2025

219.00
Save 32.35 (15%)
H51158.AD Cyclopropylmagnesium bromide, 0.5M in MeTHF, Thermo Scientific Chemicals
192.65

Online exclusive

214.00
Save 21.35 (10%)
H51158.AE Cyclopropylmagnesium bromide, 0.5M in MeTHF, Thermo Scientific Chemicals
301.65

Online exclusive

335.00
Save 33.35 (10%)
H26273.AE Cyclopropylmagnesium bromide, 0.5M solution in THF, AcroSeal™, Thermo Scientific™
232.65

Special offer

Online exclusive

Ends: 26-Sep-2025

274.00
Save 41.35 (15%)
087291.JT Ethylmagnesium bromide, 3M in ether, Thermo Scientific Chemicals
69.10
087291.JU Ethylmagnesium bromide, 3M in ether, Thermo Scientific Chemicals
108.00
041675.JT Ethylmagnesium bromide, 3M in ether, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
65.00
041675.JU Ethylmagnesium bromide, 3M in ether, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
122.00
H54840.AE Isopropylmagnesium bromide, 3M in 2-MeTHF, Thermo Scientific Chemicals
314.65

Special offer

Online exclusive

Ends: 26-Sep-2025

370.00
Save 55.35 (15%)
H51155.AE Isopropylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
127.65

Special offer

Online exclusive

Ends: 26-Sep-2025

150.00
Save 22.35 (15%)
H51155.AP Isopropylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
525.65

Online exclusive

584.00
Save 58.35 (10%)
H51156.AE Isopropylmagnesium chloride - LiCl complex, 1M in MeTHF, Thermo Scientific Chemicals
252.65

Online exclusive

280.00
Save 27.35 (10%)
H51156.AP Isopropylmagnesium chloride - LiCl complex, 1M in MeTHF, Thermo Scientific Chemicals
997.65

Online exclusive

1,108.00
Save 110.35 (10%)
087324.AP Methylmagnesium bromide, 3M in ether, Thermo Scientific Chemicals
141.65

Special offer

Online exclusive

Ends: 26-Sep-2025

166.00
Save 24.35 (15%)
041252.AE Methylmagnesium bromide, 3M in ether, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
43.65

Special offer

Online exclusive

Ends: 30-Jun-2025

50.60
Save 6.95 (14%)
041252.AP Methylmagnesium bromide, 3M in ether, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
154.65

Online exclusive

172.00
Save 17.35 (10%)
042101.JS Methylmagnesium chloride, 3M in THF, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
Contact Us ›
-
042101.JU Methylmagnesium chloride, 3M in THF, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
Contact Us ›
-
H51162.AE n-Propylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
67.20
H51162.AP n-Propylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
213.65

Special offer

Online exclusive

Ends: 26-Sep-2025

251.00
Save 37.35 (15%)
H54729.AE Phenylmagnesium bromide, 3M in 2-MeTHF, Thermo Scientific Chemicals
274.65

Special offer

Online exclusive

Ends: 30-Jun-2025

323.00
Save 48.35 (15%)
087326.AE Phenylmagnesium bromide, 3M in ether, Thermo Scientific Chemicals
65.10
087326.AP Phenylmagnesium bromide, 3M in ether, Thermo Scientific Chemicals
163.65

Special offer

Online exclusive

Ends: 30-Jun-2025

192.00
Save 28.35 (15%)
042859.AE Phenylmagnesium bromide, 3M in ether, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
62.20
042859.AP Phenylmagnesium bromide, 3M in ether, packaged under Argon in resealable ChemSeal™ bottles, Thermo Scientific Chemicals
173.65

Online exclusive

193.00
Save 19.35 (10%)
H51164.AE tert-Butylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
151.65

Special offer

Online exclusive

Ends: 30-Jun-2025

178.00
Save 26.35 (15%)
H51164.AP tert-Butylmagnesium chloride, 1M in MeTHF, Thermo Scientific Chemicals
682.65

Special offer

Online exclusive

Ends: 30-Jun-2025

803.00
Save 120.35 (15%)
H54824.AE tert-Pentylmagnesium chloride, 1M in 2-MeTHF, Thermo Scientific Chemicals
373.65

Special offer

Online exclusive

Ends: 26-Sep-2025

439.00
Save 65.35 (15%)
H54635.AE (Trimethylsilyl)methylmagnesium chloride, 0.5M in 2-MeTHF, Thermo Scientific Chemicals
136.65

Online exclusive

152.00
Save 15.35 (10%)

Resources

Support